Evidence map›Paper›PMID 41607062›Full record

ArticleJournal of microbiology and biotechnology2026

Subacute 28-Day OECD-Guided Oral Toxicity Study of

Francesco Di Pierro, Amjad Khan, Gayathri Veeraraghavan, Kalaivani Periyathambi, Sathiya Ravikumar, Maria Laura Tanda, Nicola Zerbinati, Andrea Carugno, Ikram Ujjan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of microbiology and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco Di PierroMicrobiota International Clinical Society, Torino, Italy.
Amjad KhanDepartment of Biochemistry, Liaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Pakistan.
Gayathri VeeraraghavanCentre For Toxicology and Developmental Research (CEFTE), Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai, India.
Kalaivani PeriyathambiCentre For Toxicology and Developmental Research (CEFTE), Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai, India.
Sathiya RavikumarCentre For Toxicology and Developmental Research (CEFTE), Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai, India.
Maria Laura TandaEndocrine Unit, Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Nicola ZerbinatiDepartment of Medicine and Technological Innovation, University of Insubria, Varese, Italy.
Andrea CarugnoDermatology Unit, Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Ikram UjjanDepartment of Pathology, Liaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ensuring the safety of microbial strains intended for probiotic use is essential, particularly for species such as

Indexed as

Escherichia coliImmunocompromised HostProbioticsToxicity Tests, SubacuteAdministration, OralAnimalsFecesFemaleMaleMiceMice, NudeRatsRats, WistarEscherichia coli 5CImmunocompromised modelLMG S-33222NOAELNon-pathogenic E. coliNude miceOECD 407Probiotic safetyRepeated-dose oral toxicityWistar rats

Identifiers

PMID41607062
PMCPMC12868953

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.