Observational studyFrontiers in endocrinology2025
Association between elevated C-reactive protein-triglyceride-glucose index and in-hospital major adverse cardiovascular events in acute coronary syndrome patients after percutaneous coronary intervention: a single-center prospective observational study.
Observational study in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Inflammation and metabolic disorders play important roles in the pathogenesis of acute coronary syndrome(ACS). The C-reactive protein-triglyceride-glucose index(CTI) is a novel combined inflammatory-metabolic indicator. This study aimed to evaluate the association between CTI and in-hospital major adverse cardiovascular events(MACE) in ACS patients after percutaneous coronary intervention(PCI). Methods: This prospective observational study consecutively enrolled 300 patients who underwent PCI for ACS at our hospital from January 2023 to October 2025. C-reactive protein(CRP),triglyceride(TG), and fasting plasma glucose (FPG) were measured upon admission, and CTI values were calculated. Patients were divided into Q1-Q4 groups according to CTI quartiles. The primary endpoint was in-hospital MACE, defined as a composite of cardiac death, acute stent thrombosis, recurrent myocardial infarction, acute heart failure, and cardiogenic shock. Multivariate logistic regression analysis was used to assess the association between CTI and in-hospital MACE. Results: Among the 300 patients, 73 (24. 3%) experienced in-hospital MACE. Compared with the Q1 group, patients in the Q4 group had significantly higher incidence of MACE (10. 7% Conclusion: Elevated CTI levels after PCI in ACS patients are significantly associated with increased risk of in-hospital MACE. CTI may be an effective tool for evaluating short-term prognosis in ACS patients after PCI, providing reference for early risk stratification and enhanced monitoring.
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