Evidence map›Paper›PMID 41607518›Full record

ArticlebioRxiv : the preprint server for biology2026

Distinct EBV-Associated Phenotypes Due to a Novel Homozygous Missense Variant in

Rui Yang, Solomon K Turunbedu, Sara Nandiwada, Choladda V Curry, Tarek M Elghetany, Brooks P Scull, Junnan Geng, Alexander Vargas-Hernandez, Ivan K Chinn, Sebastian Ochoa and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rui YangDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0003-4427-2158
Solomon K TurunbeduDepartment of Pathology and Laboratory Medicine, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.
Sara NandiwadaDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Choladda V CurryDepartment of Pathology and Laboratory Medicine, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.
Tarek M ElghetanyDepartment of Pathology and Laboratory Medicine, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.
Brooks P ScullTexas Children's Cancer Center, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Junnan GengDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Alexander Vargas-HernandezDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Ivan K ChinnDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Sebastian OchoaDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Carl E AllenDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Lisa Forbes SatterDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.

Funding

Tissue ResourceP50CA126752 · NCI · BAYLOR COLLEGE OF MEDICINE · PI MALCOLM K. BRENNER, HELEN E HESLOP · 2007 to 2026
$51.4M
NCI NIH HHS P50 CA126752
6 · The paper itself

Abstract

Biallelic deficiencies of CD27 and its ligand CD70 underlie selective susceptibility to Epstein-Barr virus (EBV) infection and its acute and chronic complications, underscoring their non-redundant roles in anti-EBV immunity. To date, 16 pathogenic

Identifiers

PMID41607518
PMCPMC12836332

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.