Evidence map›Paper›PMID 41608090›Full record

ArticleWorld journal of diabetes2026

Fractional carbon dioxide laser-induced photothermal activation of mesenchymal stem cell-derived exosomes accelerates diabetic wound healing by enhancing angiogenesis.

Jin-Yuan Chen, Zhe Ji, Kang Guo, Hao-Nan Wang, Chen-Chen Zhu, Tao Li, Xiang-Bin Zhao, Yu-Ting Wang, Qiang Li, Pei-Sheng Jin and 1 more

Abstract read
In one paragraph

Article in World journal of diabetes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Jin-Yuan ChenDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China.
Zhe JiDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China.
Kang GuoDepartment of Burn and Plastic Surgery, Shangqiu First People's Hospital, Shangqiu 476000, Henan Province, China.
Hao-Nan WangThe First Clinical Medical College, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China.
Chen-Chen ZhuThe First Clinical Medical College, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China.
Tao LiDepartment of Medical Cosmetology, Caoxian People's Hospital, Heze 274400, Shandong Province, China.
Xiang-Bin ZhaoDepartment of Burn and Plastic Surgery, Second Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China.
Yu-Ting WangDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China.
Qiang LiDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China.
Pei-Sheng JinDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China.
Xue-Yang LiDepartment of Plastic Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu Province, China. lmlxy240923@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExosomes (Exos) derived from mesenchymal stem cells (MSCs) have emerged as a promising therapeutic option for diabetic wound healing owing to their strong pro-angiogenic potential. Nevertheless, their relatively low bioactivity remains a major barrier to successful clinical application. Fractional CO

aimTo investigate the mechanisms through which low-energy fractional Exos derived from CO

methodsAd-MSCs were subjected to a single exposure of fractional CO

resultsFollowing a single exposure to fractional CO

conclusionLow-energy fractional CO

Indexed as

Diabetic woundExosomesFractional carbon dioxideMesenchymal stem cellsPhotothermal effectSphingosine-1-phosphate

Identifiers

PMID41608090
PMCPMC12836190

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.