ArticleWorld journal of diabetes2026
Body composition and adipokines in pregnant women: Associations with gestational diabetes mellitus risk.
Article in World journal of diabetes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundGestational diabetes mellitus (GDM) is characterized by glucose intolerance first identified during pregnancy. Adipokines are adipose-derived hormones regulating insulin sensitivity, while body composition describes the body's fat and non-fat components, which change dynamically in gestation.
aimTo explore the associations between body composition, adipokines, and GDM risk, identifying early predictive markers to enhance prenatal risk assessment.
methodsA retrospective analysis included 1656 singleton pregnant women (276 with GDM, 1380 with normal glucose tolerance) from 2020-2024. Early pregnancy (6-16 weeks) body composition was assessed
resultsGDM women had higher pre-pregnancy body mass index (BMI), glucose/insulin, homeostasis model assessment of insulin resistance, lower insulin sensitivity index (all
conclusionBody composition parameters (FMP, FMI) and adipokines (leptin, adiponectin) are closely linked to GDM risk. Integrating these assessments into prenatal care facilitates early risk identification and targeted interventions to improve maternal-fetal outcomes.
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