Evidence mapPaperPMID 41608692Full record

SynthesisFrontiers in microbiology2025

Bile microbiota in gallbladder stones and its association with

Hao Li, Huiyao Zhang, Wenyu Wu, Tingting Zhou, Xiaoxiao Chen, Yang Yang, Wei Wei

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hao Li *Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Huiyao Zhang *Guangzhou University of Chinese Medicine, Guangzhou, China.
Wenyu WuWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Tingting ZhouWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xiaoxiao ChenWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yang YangWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Wei WeiWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Gallbladder stones (GS) is a prevalent gallstone disease. Recent studies indicate that bile microbiota dysregulation may contribute to their pathogenesis. However, the specific microbial alterations and their differences from gut microbiota patterns remain unclear. This study aimed to systematically evaluate the association between bile microbiota composition and GS. Methods: Eligible studies comparing bile microbiota profiles between patients with GS and non-GS controls were retrieved from eight databases. Data on Results: For Conclusion: GS is associated with bile microbiota dysbiosis, characterized by increased richness and potential overrepresentation of dominant taxa. These alterations differ from gut microbiota patterns in GS, suggesting a unique role of bile microbiota in GS pathogenesis. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD420251028569.

Indexed as

bile microbiotagallbladder stonesHelicobacter pylorimeta-analysissystematic review

Identifiers

PMID41608692
PMCPMC12845325

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.