Evidence map›Paper›PMID 41608693›Full record

ReviewFrontiers in microbiology2025

Bile acid signaling mediates gut microbiota regulation of host lipid metabolism.

Mengkuan Liu, Cuimei He, Xinyu Lv, Wanru Zheng, Jie Yin, Yixing Li, Jie Ma

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biomedicines · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengkuan LiuGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning, China.
Cuimei HeGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning, China.
Xinyu LvGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning, China.
Wanru ZhengGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning, China.
Jie YinCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, China.
Yixing LiGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning, China.
Jie MaGuangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although advancements in the study of gut microbiota have clarified the close association between gut microbiota and the host's metabolism, the underlying mechanism remains unclear. Bile acids are important components of the host's metabolism and are deeply influenced by gut microbiota. In recent years, significant progress has been made in the study of how gut microbiota regulate their host's lipid metabolism through bile acids. This review summarizes the enterohepatic circulation of bile acids, the interaction between gut microbiota and bile acids, and the role of gut microbiota-bile acid signaling in the regulation of lipid metabolism. Finally, this review examines the effects of bile acid metabolism disorders on obesity. This review aims to provide a novel perspective for understanding the relationship between gut microbiota and the host's lipid metabolism.

Indexed as

bile acidsenterohepatic circulationgut microbiotalipid metabolismsignal pathway

Identifiers

PMID41608693
PMCPMC12845338

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.