Evidence map›Paper›PMID 41611661›Full record

ArticleNature communications2026

A quantitative, multimodal wearable bioelectronic device for comprehensive stress assessment and sub-classification.

Xiaochang Pei, Anita Ghandehari, Shingirirai Chakoma, Jerome Rajendran, Jorge Alfonso Tavares-Negrete, Rahim Esfandyarpour

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaochang Pei *Department of Electrical Engineering and Computer Science, University of California, Irvine, CA, USA.
Anita Ghandehari *Department of Electrical Engineering and Computer Science, University of California, Irvine, CA, USA.
Shingirirai Chakoma *Department of Electrical Engineering and Computer Science, University of California, Irvine, CA, USA.
Jerome Rajendran *Department of Electrical Engineering and Computer Science, University of California, Irvine, CA, USA.ORCID http://orcid.org/0000-0001-8235-6382
Jorge Alfonso Tavares-NegreteLaboratory for Integrated Nano Bio Electronics Innovation, The Henry Samueli School of Engineering, University of California, Irvine, CA, USA.ORCID http://orcid.org/0000-0001-7695-460X
Rahim EsfandyarpourDepartment of Electrical Engineering and Computer Science, University of California, Irvine, CA, USA. rahimes@uci.edu.ORCID http://orcid.org/0000-0002-4528-3601

Funding

National Science Foundation (NSF) 2538997
6 · The paper itself

Abstract

Stress is a universal experience impacting mental and physical health. However, no precise, objective wearable tool exists for continuous, long-term stress monitoring, which is essential for understanding stress-related health outcomes. To address this gap, we introduce SQC-SAS, a multimodal wearable device that simultaneously and continuously measures multiple physiological and molecular stress biomarkers for quantitative stress assessment and sub-classification. This device features exceptional environmental stability, reusability, and fully wireless data and power operation. Machine learning enables data-driven stress assessment and classification across multiple stress states, allowing biomarker profiles to be correlated with each state. Its wristband-like design enables continuous stress monitoring and real-time visualization. We envision our wearable will greatly advance precise, objective stress assessment and monitoring, offering unprecedented capabilities and laying the foundation for personalized interventions and a deeper understanding of stress-related outcomes.

Indexed as

Stress, PhysiologicalStress, PsychologicalWearable Electronic DevicesBiomarkersDigital HealthHumansMachine LearningMonitoring, PhysiologicWireless TechnologyBiomarkers

Identifiers

PMID41611661
PMCPMC12858848

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.