ArticleNature2026
Developmental convergence and divergence in human stem cell models of autism.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Pathological Priming and Developmental Heterochrony as Organizing Concepts in Human iPSC Models of Autism Spectrum Disorder.Molecular neurobiology · 2026Review
- Systematic CRISPRi perturbation of 1,408 autism risk genes maps multilevel transcriptional convergence in human cortical neurons.bioRxiv : the preprint server for biology · 2026Article
- Organoid intelligence: a promising paradigm for autism spectrum disorder research.Molecular psychiatry · 2026Review
- Genetic Heterogeneity in Autism Spectrum Disorder: Diagnostic Yield, Recurrent Genes, and Rare Variant-Phenotype Associations from Whole-Exome Sequencing.International journal of molecular sciences · 2026Article
- Characterization of Electrophysiological and Transcriptomic Alterations in Patient-Derived Neurons from CHAMP1 Syndrome.bioRxiv : the preprint server for biology · 2026Article
- Signaling Through Girdin Underlies Excessive Cell Morphogenesis Resulting from Depletion of Neurodevelopmental Disorder-Related Neurexin-2.International journal of molecular sciences · 2026Article
- Multi-omics profiling reveals MAGEL2-driven defects in human corticogenesis shared across Prader-Willi and Schaaf-Yang syndromes.bioRxiv : the preprint server for biology · 2026Article
- Interactome mapping in human excitatory neurons reveals novel risk genes and pathways in Alzheimer's disease.bioRxiv : the preprint server for biology · 2026Article
- Article
- Single-cell atlas of the developing Down syndrome brain cortex.Nature medicine · 2026Article
- Article
- Female iPSC X-chromosome inactivation (XCI) erosion and its transcriptomic effects during CRISPR gene editing and neural differentiation.bioRxiv : the preprint server for biology · 2026Article
- Convergent effects of neurodevelopmental disorder-associated variants at mitochondria.bioRxiv : the preprint server for biology · 2026Article
- Multiple autism genes influence GABA neuron remodeling via distinct developmental trajectories.Genetics · 2025Article
- Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate.bioRxiv : the preprint server for biology · 2025Article
- Multiple autism genes influence GABA neuron remodeling via distinct developmental trajectories.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Aaron Gordon *Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Se-Jin Yoon *Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0001-8412-5991
Lucy K Bicks *Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Jacqueline M MartínProgram in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-4181-4970
Greta PintacudaStanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA.ORCID 0000-0001-5126-2279
Stephanie ArteagaProgram in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Brie WamsleyProgram in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Qiuyu GuoProgram in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Lubayna ElahiDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Ricardo E DolmetschTempero Bio, Boston, MA, USA.
Jonathan A BernsteinDepartment of Pediatrics, Stanford University, Stanford, CA, USA.ORCID 0000-0001-5369-346X
Ruth O'HaraDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Joachim F HallmayerDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
Kasper LageStanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA.ORCID 0000-0001-6827-6239
Sergiu P PascaDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA. spasca@stanford.edu.ORCID 0000-0002-3216-3248
Daniel H GeschwindProgram in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA. dhg@mednet.ucla.edu.ORCID 0000-0003-2896-3450
Funding
UCLA High-Throughput Neuropsychiatric Disorder Phenotyping Center (UCLA HT-NPC)RM1MH132651 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DANIEL H GESCHWIND, BENNETT G NOVITCH · 2023 to 2026
$6.5MCross modal integration of molecular and physiological networks in ASD (2/2)U01MH115745 · NIMH · STANFORD UNIVERSITY · PI PASCA, SERGIU · 2017 to 2021
$4.0M2/3 Integrative Genomic Analysis of Human Brain Development and AutismR01MH110927 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GESCHWIND, DANIEL H · 2016 to 2019
$2.7M1/3 Building integrative CNS networks for genomic analysis of autismR01MH109912 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GESCHWIND, DANIEL H · 2016 to 2020
$2.6MNIMH NIH HHS R01 MH109912NIMH NIH HHS R01 MH110927NIMH NIH HHS RM1 MH132651NIMH NIH HHS U01 MH115745
Abstract
Two decades of genetic studies in autism spectrum disorder (ASD) have identified more than 100 genes harbouring rare risk mutations
Indexed as
Autism Spectrum DisorderInduced Pluripotent Stem CellsModels, BiologicalCell DifferentiationCell LineCRISPR-Cas SystemsFemaleHumansMaleMutationNeural Stem CellsOrganoidsProtein Interaction MapsTranscriptome
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.