Evidence map›Paper›PMID 41612431›Full record

ArticleJournal of nanobiotechnology2026

Optimization of M1 macrophage targeting using a glucosylated albumin nanoplatform for ROS scavenging and mitochondrial rescue in acute kidney injury.

Ji Yong Park, Jung Nam An, Seong Min Lee, Young Chan Ann, Eunjin Bae, Kyung Don Yoo, Yong Chul Kim, Hyeri Chae, Joo Yeon Oh, Ran Ji Yoo and 5 more

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ji Yong Park *Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea.
Jung Nam An *Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.
Seong Min LeeDepartment of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Young Chan AnnInstitute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea.
Eunjin BaeDepartment of Internal Medicine, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.
Kyung Don YooDepartment of Internal Medicine, Ulsan University Hospital, Seoul, Republic of Korea.
Yong Chul KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Hyeri ChaeDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Joo Yeon OhBiomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.
Ran Ji YooDepartment of Nuclear Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Dong Ki KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Sung Hyun HongClichembio Inc, Seoul, Republic of Korea.
Yon Su KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea. yonsukim@snu.ac.kr.
Yun-Sang LeeInstitute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea. wonza43@snu.ac.kr.
Seung Hee YangBiomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea. ysh5794@snu.ac.kr.

Funding

Korea Health Industry Development Institute HI23C107200Ministry of SMEs and Startups RS-2023-00304101Ministry of SMEs and Startups RS-2024-00419832National Research Foundation of Korea 2021R1A2C300942714National Research Foundation of Korea RS-2023-NR077156National Research Foundation of Korea RS-2024-00464001
6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) remains a major clinical challenge resulting from the intertwined processes of oxidative stress and macrophage-driven inflammation, both converging on mitochondrial dysfunction. We developed a glucosylated albumin nanoplatform (Glc

resultsPhysicochemical characterization confirmed reproducible synthesis with defined degrees of functionalization and stable physicochemical properties. In vitro, Glc

conclusionsGlc

Indexed as

Acute Kidney InjuryAlbuminsMacrophagesMitochondriaNanoparticlesReactive Oxygen SpeciesAnimalsHumansKidneyMaleMembrane Potential, MitochondrialMiceMice, Inbred C57BLOxidative StressReperfusion InjuryAlbuminsReactive Oxygen SpeciesAcute kidney injuryAlbumin nanoplatformIschemia–reperfusion injuryMacrophagesMitochondrial dysfunctionOxidative stress

Identifiers

PMID41612431
PMCPMC12924581

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.