ReviewFundamental research2025
Nanoscale synthetic biology with innovative medicinal applications.
Review in Fundamental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Accelerating the clinical translation of bioengineered anticancer therapeutics.Journal of the National Cancer Center · 2026Article
- Article
- Plying potency assays for immunotherapy of solid tumors.Frontiers in immunology · 2026Review
- Nano-synthetic biology for disease diagnosis and treatment.Fundamental research · 2025Article
- Biodegradable and Stimuli-Responsive Nanomaterials for Targeted Drug Delivery in Autoimmune Diseases.Journal of functional biomaterials · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The rapid advancement of synthetic biology and nanoscience has given rise to a new research field, known as nanoscale synthetic biology (NSB). This field emphasizes the interactions and coordination within entire biological systems, with the goal of achieving more efficient and controllable biological engineering through nanoscale manipulation. Nanocarriers facilitate the delivery of gene-regulating systems (such as CRISPR, mRNA, siRNA, and plasmids), nanozymes, drugs, and specific nanoprobes, enabling precise control over gene expression, modulation of biological metabolism, and monitoring of synthesized products in various organisms (including cells, bacteria, and viruses). This enables advancements in disease treatment, biological imaging, biocatalysis, and biosensing. Moreover, genetically engineered biological products can be employed in the construction of biomimetic nanocarriers with tailored functionalities, thereby fostering a virtuous cycle between nanoscience and synthetic biology. This review delves into the applications of NSB within the biomedical field, providing insight into common nanocarriers, nano-bio assembling systems, and specific NSB applications. We hope this review aids researchers in deepening their understanding of the interactions between organisms and nanomaterials, ultimately leading to the development of more innovative biological applications, the advancement of scientific technology, and contributions to addressing significant societal challenges.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.