ArticleCureus2025
Clinical Outcomes of Two Versions of the Ahmed Glaucoma Valve FP7 in Glaucoma Patients.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe primary goal of surgical treatment for glaucoma is the sustained reduction of intraocular pressure (IOP). The Ahmed® Glaucoma Valve (AGV) (New World Medical, Inc., Rancho Cucamonga, CA) is a surgically implanted drainage device that allows bidirectional aqueous humor outflow and IOP regulation. Although multiple generations of the AGV have been developed, comparative studies evaluating patient outcomes remain limited. This retrospective study aimed to compare clinical outcomes following implantation of two different generations of the AGV FP7 in patients with complicated, refractory glaucoma. MATERIALS AND
methodsThis retrospective study analyzed preoperative and postoperative clinical data from glaucoma patients who underwent AGV FP7 implantation at the Eye Clinic of St. Johannes Hospital in Dortmund, Germany. Two cohorts were compared: group A, treated with an earlier AGV FP7 model between January 2008 and December 2012 (n = 159 eyes), and group B, treated with a newer AGV FP7 model between January 2019 and December 2020 (n = 109 eyes). The newer version features a highly polished surface designed to reduce friction and tissue reaction, whereas the earlier model has a comparatively rougher surface. Clinical outcomes were assessed over a one-year follow-up period and included IOP reduction, number of antiglaucoma medications, changes in visual acuity, postoperative complications, need for reoperation, and overall therapeutic success.
resultsOne year postoperatively, IOP reduction was significantly greater in group B (52.5%) compared to group A (42.4%). Despite this difference, the therapeutic target was achieved in both groups. The number of required topical antiglaucoma medications also decreased significantly following AGV implantation by 56.8% in group A and 68.6% in group B. The most common complication at discharge was ocular hypotony, observed in 30.8% of cases in group A and 19.6% in group B. However, no cases of persistent hypotony were reported in either group at the one-year follow-up.
conclusionBoth the earlier and newer versions of the AGV FP7 effectively provided sustained IOP reduction in patients with refractory glaucoma. Although the newer generation demonstrated a greater IOP reduction and was associated with fewer short-term complications, including hypotony, choroidal detachment, and endothelial touch, overall therapeutic success remained high in both groups.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.