ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026
Obstetrical outcomes in pregnant patients following a gluten-free diet: A prospective cohort study.
Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveConcerns have been raised about the nutritional adequacy of a gluten-free (GF) diet during pregnancy, specifically in the absence of celiac disease, and its impact on fetal development. The objective of this study was to investigate the association between a GF diet during pregnancy and obstetrical outcomes, with further sensitivity analyses exploring those without celiac disease.
methodsUsing data from the ongoing P3 Cohort study, self-reported data were obtained on participant demographics, GF diet, celiac disease, and obstetrical outcomes. Fisher exact, χ
resultsOf the 2359 participants included, 108 (4.6%) reported following a GF diet in pregnancy. The majority of these individuals (n = 68, 63.0%) were non-celiac. Participants in the GF group were older, more likely to identify as white, and more likely to take prenatal vitamin B supplements. There were no significant differences in obstetrical outcomes between the GF and non-GF participants. Sensitivity analyses excluding patients with celiac disease demonstrated similar results, with no difference in obstetrical outcomes observed.
conclusionFollowing a GF diet in pregnancy, even in individuals without celiac disease, was not associated with adverse obstetrical outcomes. These results provide some reassurance on the safety of a GF diet in pregnancy but require validation in larger studies.
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