Evidence mapPaperPMID 41614539Full record

ReviewEuropean stroke journal2026

Stroke Action Plan for Europe 2018-2030 (SAP-E): mid-term review and update.

Hanne Christensen, Francesca Romana Pezzella, Melinda Berg Roaldsen, Aleš Tomek, Arlene Wilkie, Louisa Christensen, Martin Dichgans, Avril Drummond, Tiina Laatikainen, Carlos A Molina and 86 more

Erratum issuedAbstract readReview
In one paragraph

Review in European stroke journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

96 authors.

Hanne ChristensenDepartment of Neurology, Copenhagen University Hospital, Bispebjerg, Copenhagen, Denmark.ORCID 0000-0002-7472-3194
Francesca Romana PezzellaDepartment of Neuroscience, San Camillo-Forlanini Hospital, Rome, Italy.
Melinda Berg RoaldsenClinical Research Department, University Hospital of North  Norway, Tromsø, Norway.
Aleš TomekNeurology Department, Second Medical Faculty of Charles University and University Hospital Motol, Prague, Czech Republic.
Arlene WilkieStroke Alliance for Europe, London, United Kingdom.
Louisa ChristensenDepartment of Neurology, Copenhagen University Hospital, Bispebjerg, Copenhagen, Denmark.ORCID 0000-0003-1448-5646
Martin DichgansLMU Clinic, Institute for Stroke and Dementia Research, Munich, Germany.ORCID 0000-0002-0654-387X
Avril DrummondSchool of Health Sciences, University of Nottingham, Nottingham, United Kingdom.
Tiina LaatikainenInstitute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.ORCID 0000-0002-6614-4782
Carlos A MolinaHospital Vall d'Hebron, Barcelona, Catalonia.
Katharina S SunnerhagenDepartment of Rehabilitation Medicine, University of Gothenburg, Gothenburg, Sweden.
Danilo ToniUniversity La Sapienza, Rome, Italy.
Sonia AbilleiraMinistry of Health, Stroke Programme for Catalonia, Fundació TIC Salut Social, Bracelona, Catalonia.
Diana Aguiar de SousaLisbon Central University Hospital, ULS São José, Lisbon,  Portugal.
Anita ArsovskaStroke Center, University Clinic of Neurology, University "Ss. Cyril and Methodius," Faculty of Medicine, Skopje, North Macedonia.
Heinrich AudebertDepartment of Neurology and Center for Stroke Research, Charité Universitaetsmedizin, Berlin, Germany.
Jelena BartolovicUniversity Hospital Sveti Duh, Zagreb, Croatia.
Yannick BéjotDepartment of Neurology, Dijon University Hospital, Dijon, France.
Geert Jan BiesselsDepartment of Neurology, UMC  Utrecht, Utrecht, The Netherlands.
Juliet BouverieStroke Association, London, United Kingdom.
Hrvoje BudincevicDepartment of Neurology, Sveti Duh University Hospital, Zagreb, Croatia.ORCID 0000-0002-0184-8949
Barbara CasollaDepartment of Neurology, Université Cote d'Azur UR2CA-URRIS, CHU Hôpital Pasteur 2, Nice, France.
Hugues ChabriatDepartment of Neurology, CNVT (APHP) and INSERM, University of Paris Cité, Paris, France.
Marina CharalambousDepartment of Rehabilitation Sciences, Cyprus University of Technology, Limassol, Cyprus.
Jesse DawsonSchool of Cardiovascular and Metabolic Health College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Stephanie DebetteDepartment of Epidemiology and Neurology, University of Bordeaux, Bordeaux University Hospital, Inserm, Bordeaux, France.ORCID 0000-0001-6950-984X
Frank-Erik de LeeuwDepartment of Neurology, Research Institute for Medical Innovation, Radboudumc, Nijmegen, The Netherlands.
Adam DenesHUN-REN Institute of Experimental Medicine, Budapest, Hungary.
Marina DiomediUniversity Hospital of Rome Tor Vergata, Rome, Italy.
Diederik DippelDepartment of Neurology, Erasmus MC Stroke Center Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Ulrich DirnaglDepartment of Experimental Neurology, Charite Universitätsmedizin Berlin and Berlin Institute of Health, Berlin, Germany.
Urs FischerDepartment of Neurology, University Hospital Bern and University of Bern, Bern, Switzerland.ORCID 0000-0003-0521-4051
Yuriy FlominDepartment of Neurology, Shupyk National University of Healthcare of Ukraine and Medical Center "Universal Clinic 'Oberig'", Kyiv, Ukraine.
Ana Catarina FonsecaDepartment of Neurology, Hospital de Santa Maria, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
Birgitte ForchammerDanish Stroke Association, Copenhagen, Denmark.
Anne ForsterUniversity of Leeds, Leeds, United Kingdom.
Giovanni FrisulloDepartment of Neurology, Fondazione Policlinico Agostino Gemelli, IRCCS - Department of Neuroscience, Catholic University of the Sacred Heart, Rome, Italy.
Miquel GalofreFaculty of Medicine and Health, Department of Neurology and Rehabilitation, Örebro University, Örebro, Sweden.
Zuzana GdovinováDepartment of Neurology, P.J. Safarik University Kosice, Faculty of Medince and University Hospital L. Pasteur Kosice, Slovakia.
Christoph GumbingerDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0002-6137-1169
Joseph HarbisonDepartment of Medical Gerontology, Trinity College Dublin and Irish National Audit of Stroke, Dublin, Ireland.ORCID 0000-0003-3680-5751
Richard HobbsUniversity of Oxford, Oxford, United Kingdom.ORCID 0000-0001-7976-7172
Dalius JatuzisInstitute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Hrvoje JurlinaStroke Survivor, Stroke Alliance for Europe, Faculty of Family medicine, Zagreb Medical School, Zagreb, Croatia.
Mira KatanDepartment of Neurology, University Hospital of Basel, Basel, Switzerland.
Lisa KiddDepartment of Nursing, School of Health & Life Sciences, Glasgow Caledonian University, Glasgow, United Kingdom.
Stefan KiechlDepartment of Neurology, Medical University of Innsbruck, , VASCage, Innsbruck, Austria.ORCID 0000-0002-9836-2514
Janika KõrvDepartment of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia.
Christina KruuseDepartment of Brain and Spinal Cord Injury, Neuroscience Center, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Wilfried LangMedical Faculty, Sigmund Freud Private University, Vienna, Austria.
Arthur LieszDepartment of Neurology, LMU Hospital, Munich, Germany.ORCID 0000-0002-9069-2594
Svetlana LorenzanoDepartment of Human Neurosciences, Sapienza, University of Rome, Rome, Italy.
Andreas LuftCereneo Center for Neurology and Rehabilitation, University Hospital Zurich, Vitznau, Switzerland.
Grethe LundeStroke Survivor, Stroke Alliance for Europe, Norway.
Chris MaceyStroke Alliance for Europe, London, United Kingdom.
Hugh Stephan MarkusUniversity of Cambridge, Cambridge, United Kingdom.
Gillian MeadStroke and Elderly Care Medicine, University of Edinburgh and NHS Lothian, Edinburgh, United Kingdom.
Patrik MichelDepartment of Neurology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-4954-7579
Serefnur OzturkDepartment of Neurology, Selcuk University Faculty of Medicine, Konya, Turkey.
Maurizio PaciaroniDepartment of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy.
Aleksandra PavlovicDepartment of Neurology, Faculty of Special Education and Rehabilitation, University of Belgrade, Belgrade, Serbia.
Carina U PerssonDepartment of Neuroscience and Physiology, Rehabilitation Medicine, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Terence J QuinnDepartment of Geriatric Medicine, University of Glasgow, Glasgow, United Kingdom.
Peter RothwellDepartment of Neurology, University of Oxford, Oxford, United Kingdom.
Luca SabaDepartment of Radiology, AOU  Cagliari, Cagliari, Italy.
Paola SantaluciaDepartment of Neurology, Staff Direzione Strategica, AOSGA, Roma, Italy.
Gustavo SantoDepartment of Neurology, Hospitais da Universidade de Coimbra, Unidade Local de Saúde, Coimbra, Portugal.
Claus SimonsenDepartment of Neurology, Aarhus University Hospital, Aarhus, Denmark.
Thorsten SteinerDepartment of Neurology, Varisano Krankenhaus Frankfurt Höchst, Frankfurt, Germany.
Katarzyna Stolarz-SkrzypekFirst Department of Cardiology and Hypertension, Jagiellonian University Medical College, Krakow, Poland.
Cristina TiuDepartment of Clinical Neurosciences, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.
Alexander TsiskaridzeIvane Javakhishvili Tbilisi State University, Pineo Medical Ecosystem, Tbilisi, Georgia.
Georgios TsivgoulisSecond Department of Neurology, "Attikon" University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-0640-3797
Jaakko TuomilehtoDepartment of Public Health, University of Helsinki, Helsinki, Finland.
Teresa UlbergDepartment of Neurology, Skåne University Hospital in Malmö/Lund, Malmö, Sweden.
Paolo UrsilloDepartment of Hygiene and Public Health, Agenas-Italian Agency for Regional Health Services, Rome, Italy.
Antonella UrsoDepartment of Health Economics, Health Department of the Lazio Region, Rome, Italy.
Mia van EulerClinical Research Department, University Hospital of Northern Norway, Tromsø, Norway.
Margus ViigimaaCenter of Cardiology, Tallinn University of Technology, North Estonia Medical Centre, Tallinn, Estonia.
Denis VivienDepartment of Neurobiology, Centre Hospitalier Universitaire Caen Normandie, Caen, France.
Markus WagnerGerman Stroke Foundation, Gladbeck, Germany.
Marion WalkerDepartment of Stroke Rehabilitation, University of Nottingham, Nottingham, United Kingdom.
Alastair WebbDepartment of Stroke Medicine, Department of Brain Sciences, Imperial College London, London, United Kingdom.
Diana Wong RamosPortugal AVC-União de Sobreviventes, Familiares e Amigos, Lisbon, Portugal.
Mauro ZampoliniDepartment of Neurology and Physical and Rehabilitation Medicine, Department of Rehabilitation, USLUMBRIA2, Foligno, Italy.
Marialuisa ZeddeStroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Gary FordRadcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Peter KellyDepartment of Stroke Service, Mater University Hospital, Dublin, Ireland.
Robert MikulikDepartment of Neurology, International Clinical Research Center, St Anne's University Hospital, Masaryk University Brno, Brno, Czech Republic.
Bo NorrvingDepartment of Neurology, Lund University Department of Clinical Sciences Lund, Skåne University Hospital, Lund, Sweden.
Hariklia ProiosDepartment of Neurocognitive Disorders and Rehabilitation, Department of Educational and Social Policy, University of Macedonia, Thessaloniki, Greece.
Simona SaccoDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.ORCID 0000-0003-0651-1939
Else SandsetDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Joanna WardlawCentre for Clinical Brain Sciences, University of Edinburgh, UK and UK Dementia Research Institute Centre, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0002-9812-6642
Aleksandras VilionskisStroke Center, Republican Vilnius University hospital, Vilnius, Lithuania.
Valeria CasoDepartment of Emergency and Cardiovascular Medicine, Santa Maria Della Misericordia, Perugia, Italy.ORCID 0000-0002-2020-8891

Funding

ESO
6 · The paper itself

Abstract

objectivesImplementation of the Stroke Action Plan for Europe (2018-2030) (SAP-E) was initiated in 2019. It is now updated at mid-term to reflect and respond to challenges for stroke care in Europe in 2025.

methodsThe SAP-E covers the entire chain of stroke care. The sections (state of the art, current status and targets) were developed by working groups and finalised based on inputs from the Interim Review Committee and an open online meeting. Targets for 2030 were updated to reflect current knowledge, to prioritise and to increase accountability.

resultsAll sections have been updated based on the newest evidence to reflect the state of the art and current status in 2025.

conclusionStroke remains a significant health issue in Europe, with notable incidence and inequities in access to care. Key interventions are strongly evidence-based, cost-effective and supported by World Health Organization and European Union recommendations. Despite improvements, gaps remain across the care pathway but particularly in terms of access to stroke units, rehabilitation and follow-up. To control and reduce the burden of stroke, the main action points are: (1) national stroke plans, which encompass the entire chain of care and are reflected in reimbursement systems, (2) quality and outcome control, where impact is measured at both individual and health care system level, (3) robust and resilient health care organisation covering the entire chain of care that promotes equal access to sustainable, timely and evidence-based stroke care and (4) effective national strategies to promote and facilitate a healthy lifestyle and risk factor control.

Indexed as

StrokeEuropeHumansepidemiologyEuropepreventionquality assurancestrategic planningstrokestroke servicestreatiestreatment

Identifiers

PMID41614539
PMCPMC12866651

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.