Evidence map›Paper›PMID 41614832›Full record

ArticleCurrent issues in molecular biology2025

Turkish Hazelnut Extracts Exert Anti-Proliferative and Anti-Cancer Effects on Colorectal Cancer HCT-116 Cells.

Banu Bayram, Evren Demircan, Atefeh Karimidastjerd, Elvan Yılmaz Akyüz, Yusuf Tutar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Transcriptional Reprogramming of Cancer Metabolism:International journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Banu BayramDepartment of Nutrition and Dietetics, Faculty of Health Sciences, University of Health Sciences, Istanbul 34668, Türkiye.
Evren DemircanDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Istanbul 34469, Türkiye.
Atefeh KarimidastjerdDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, Istanbul 34210, Türkiye.ORCID 0000-0003-2163-2608
Elvan Yılmaz AkyüzDepartment of Nutrition and Dietetics, Faculty of Health Sciences, University of Health Sciences, Istanbul 34668, Türkiye.ORCID 0000-0002-1878-9412
Yusuf TutarDepartment of Basic Medical Sciences, Division of Biochemistry, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize 53100, Türkiye.ORCID 0000-0003-2613-9644

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rising incidence of cancer has demanded the development of new anti-cancer chemical sources. The presence of phenolics in hazelnut cell cultures has led to the development of new and potential pharmacotherapeutic uses. Hazelnut extract has emerged as a promising candidate due to its high phytochemical content. HCT-116 colorectal cancer IC

Indexed as

anticancerapoptosiscolorectal cancerhazelnut extractmitochondrial membrane potential

Identifiers

PMID41614832
PMCPMC12840033

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.