Evidence map›Paper›PMID 41614883›Full record

ArticleCurrent issues in molecular biology2025

Investigation of the Correlation Between Selected miRNAs, Proinflammatory Cytokines, and Serum Trace Elements in Bladder Cancer Development and Progression.

Arzu Ay, Nevra Alkanli, Engin Atli, Hakan Gurkan, Pinar Koroglu, Hasan Can Kuvan, Muhidin Hassan Ibrahim, Gokhan Cevik, Necdet Sut

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Arzu AyDepartment of Biophysics, Faculty of Medicine, Trakya University, Edirne 22030, Türkiye.ORCID 0000-0002-8412-091X
Nevra AlkanliDepartment of Biophysics, Faculty of Medicine, Haliç University, Istanbul 34060, Türkiye.ORCID 0000-0002-3745-8838
Engin AtliDepartment of Medical Genetics, Faculty of Medicine, Trakya University, Edirne 22030, Türkiye.ORCID 0000-0002-3937-5243
Hakan GurkanDepartment of Medical Genetics, Faculty of Medicine, Trakya University, Edirne 22030, Türkiye.ORCID 0000-0002-8967-6124
Pinar KorogluDepartment of Histology and Embryology, Faculty of Medicine, Haliç University, Istanbul 34060, Türkiye.ORCID 0000-0002-3408-7867
Hasan Can KuvanDepartment of Urology, Faculty of Medicine, Trakya University, Edirne 22030, Türkiye.ORCID 0000-0002-8160-8653
Muhidin Hassan IbrahimDepartment of Urology, Faculty of Medicine, Trakya University, Edirne 22030, Türkiye.ORCID 0000-0003-3702-5845
Gokhan CevikDepartment of Urology, Faculty of Medicine, Trakya University, Edirne 22030, Türkiye.ORCID 0000-0001-5221-5132
Necdet SutDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, Trakya University, Edirne 22030, Türkiye.ORCID 0000-0001-6678-482X

Funding

Trakya University Scientific Research Projects Unit (TUBAP) 2022/176
6 · The paper itself

Abstract

In our study, we aimed to investigate the relationship between miRNA-21, miRNA-155, miRNA-34a, IL-6, TGF-β, and TNF-α expression levels and serum trace element levels in the development and progression of bladder cancer. RT-PCR was used to establish miRNA-21, miRNA-155, and miRNA-34a expression levels while serum IL-6, TGF-β, and TNF-α levels were determined using the ELISA and measured with an atomic absorption spectrophotometer. In the patient group, miRNA-21 and miRNA-155 expression levels were significantly higher compared with the healthy control group (

Indexed as

biomarkerbladder cancermicroRNAproinflammatory cytokinetrace element

Identifiers

PMID41614883
PMCPMC12840327

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.