Evidence map›Paper›PMID 41615959›Full record

ArticlePloS one2026

Extended thrombotic prophylaxis in COVID-19 early discharge: A retrospective cohort study.

Sebastiaan T Van't Hoff, Gea Helfrich, Sanne Boerman, Hans A Hardeman

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sebastiaan T Van't HoffDepartment of Pulmonary Medicine, Amphia Hospital, Breda, the Netherlands.ORCID https://orcid.org/0009-0005-8845-2515
Gea HelfrichDepartment of Pulmonary Diseases, Maasstad Hospital, Rotterdam, the Netherlands.
Sanne BoermanDepartment of Pulmonology, St. Antonius Hospital, Nieuwegein, the Netherlands.
Hans A HardemanDepartment of Pulmonology, St. Antonius Hospital, Nieuwegein, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION/

backgroundDue to limits in available staff and space during the COVID-19 pandemic, home monitoring programmes were introduced, reducing strain on resources, and preventing readmissions. Several hospitals included prophylaxis for venous thrombotic events (VTE), as COVID-19 appeared to be thrombogenic. Other hospitals did not, expecting patients to be more mobile while at home. Our aim was to determine whether the administration of nadroparin has led to a difference in VTE occurrence between two groups of previously included patients. MATERIALS AND

methodsRetrospective cohort study of two cohorts included in home monitoring with the same protocol, except for nadroparin prophylaxis.

results663 patients were analysed in equal groups from two hospitals. No significant difference was found in occurrence of VTE after discharge, readmissions in general or readmissions due to VTE in otherwise comparable groups. DISCUSSION: As opposed to trials determining thrombotic prophylaxis was of benefit after discharge due to COVID-19, we found no difference between our groups. Our study was retrospective and comprised data compiled over almost two years, which provides a relatively large sample size and overview through different treatment regimes.

conclusionFor the future, thrombotic prophylaxis for COVID-19 home monitoring might not be indicated and reconsidered for different home monitoring programmes.

Indexed as

AnticoagulantsCOVID-19NadroparinVenous ThromboembolismVenous ThrombosisAgedFemaleHumansMaleMiddle AgedPatient DischargePatient ReadmissionRetrospective StudiesSARS-CoV-2AnticoagulantsNadroparin

Identifiers

PMID41615959
PMCPMC12857994

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.