ArticleAntonie van Leeuwenhoek2026
In vitro probiotic properties and anti-Vibrio activity of Bacillus subtilis B13 and its ethyl acetate extract.
Article in Antonie van Leeuwenhoek, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Genomic and pan-genomic analyses of Bacillus subtilis B13 provide insights into biosynthetic potential and genetic traits associated with environmental adaptation.Antonie van Leeuwenhoek · 2026Article
- Integrated Multi-Omics Characterization of Bacillus altitudinis B16 as a Potential Probiotic in Aquaculture.Current microbiology · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
This study is carried out to examine the in vitro probiotic properties of Bacillus subtilis B13 (= VTCC 910231), isolated from brackish water in the Cau Hai lagoon, Vietnam. The strain was confirmed to be safe, showing no hemolytic activity and exhibiting strong biofilm formation. It demonstrated notable environmental adaptability, growing across a wide pH range (5-9), showing moderate tolerance at 7% NaCl. B13 produced multiple extracellular enzymes, with the highest activities observed for lipase, protease, and cellulase, and additionally metabolized 25 of the 49 carbohydrates tested (51.0%). Antibiotic susceptibility profiling revealed broad sensitivity, with resistance detected to only 4 of 15 antibiotics, and it was highly sensitive to fluoroquinolones and phenicols. The ethyl acetate extract of its cell-free culture supernatant displayed noticeable inhibitory activity against five Vibrio species, which exhibited inhibition diameters varying from 13.3 ± 0.6 to 21.7 ± 0.6 mm. Moreover, the extract exhibited significant anti-inflammatory effects, achieving concentration-dependent nitric oxide inhibition (IC
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Registered trials
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