Trial reportAmerican journal of preventive medicine2026
The Impact of a Community Health Worker-Led Lifestyle-Social Determinants Program on Pacific Islander Cardiometabolic Health.
Trial report in American journal of preventive medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06471595 (Peau o le Vasa), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Peau o le Vasa: Accelerating the Currents of Health Equity for Pasifika People
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Authors and funding
12 authors.
Funding
Abstract
introductionNative Hawaiians/Pacific Islanders face disproportionate burdens of cardiometabolic diseases. This study assessed the feasibility and effectiveness of the PILI Pasifika Program, a culturally grounded, community health worker-led lifestyle intervention that targets social determinants of health to improve cardiometabolic risk factors among Native Hawaiians/Pacific Islander adults. STUDY
designA parallel-group RCT with an education material-only waitlist control was conducted. Implementation feasibility was assessed through interviews with community health workers, and participant acceptability was assessed through survey. SETTING/
participantsAcross four U.S. states and 2 U.S.-affiliated Pacific Islands, 24 community health workers recruited and delivered the PILI Pasifika Program to 242 Native Hawaiians/Pacific Islander adults with ≥1 cardiometabolic risk factor (130 intervention, 112 control) and assessed cardiometabolic, behavioral, and social determinants of health outcomes.
interventionPILI Pasifika Program consisted of 12 weekly sessions, adapted from the Diabetes Prevention Program and augmented with social determinants of health-focused activities.
main outcome measuresWeight, HbA1c, blood pressure, high-density lipoprotein, low-density lipoprotein, and total cholesterol were the outcome measures. Data were collected from 2024 to 2025 and analyzed in 2025.
resultsPILI Pasifika Program participants compared with controls showed significant reductions in weight (-2.8 vs +0.5 kg), HbA1c (-0.8% vs +0.1%), systolic (-5.7 vs +2.6 mmHg) and diastolic (-3.4 vs +1.3 mmHg) blood pressure, low-density lipoprotein (-4.7 vs +7.6 mg/dL), and total cholesterol (-9.7 vs +9.4 mg/dL). Intervention participants also showed significant improvements in fruit/vegetable intake, physical activity, food literacy, social support, housing stability, and overall well-being. Community health workers and participants found the PILI Pasifika Program highly feasible, culturally relevant, and adaptable.
conclusionsThe PILI Pasifika Program, delivered by culturally competent community health workers, improved cardiometabolic, behavioral, and social determinants of health outcomes among Native Hawaiians/Pacific Islander adults and shows promise for scalable, sustainable implementation across diverse Native Hawaiians/Pacific Islander communities.
trial registrationThis study is registered at ClinicalTrials.gov (NCT06471595).
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