← Other lipid agents × cardiovascular events

TrialLipids in health and disease2026

Association of fenofibrate therapy with cardiovascular events and mortality in diabetes patients with early-diagnosed hyperlipidemia.

Huidan Liu et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedrandomised · 3,861 people · 2026

Randomised comparison

Reduced deaths

−43%−59% to −21%

Bigger than 9 in 10 for all-cause mortality

As reported

HR 0.57, 95% CI 0.41–0.79 · the paper's word: All-cause mortality

Randomised comparison

Reduced cardiovascular events

−31%−45% to −12%

Bigger than 7 in 10 for cardiovascular events

As reported

HR 0.69, 95% CI 0.55–0.88

Randomised comparison

Reduced cardiovascular events

−53%−70% to −26%

Bigger than 9 in 10 for cardiovascular events

As reported

HR 0.47, 95% CI 0.30–0.74

Range includes no effect

No clear effect on deaths

+12%−19% to +55%

Bigger than 3 in 10 for all-cause mortality

As reported

HR 1.12, 95% CI 0.81–1.55 · the paper's word: All-cause mortality

+1 more in the walkthrough ↓

Five numbers in the abstract

the abstract, start to end

… risk in the early-diagnosed group (HR = 0.57, 95% CI 0.41-0.79) but not in the late-diagnosed group (HR = 1.12, 95% CI 0.81-1.55; P for …

… risk in the early-diagnosed group (HR = 0.69, 95%CI 0.55-0.88), with a non-significant trend in the late-diagnosed group (HR = 0.86, 95%CI 0.64-1.16; P for …

… early-diagnosed hyperlipidemia group (HR 0.47, 95% CI 0.30-0.74; P for …

← favours treatmentfavours comparator →

could be chance

All-cause mortality

HR 0.570.41–0.79

Cardiovascular events

HR 0.690.55–0.88

All-cause mortality

HR 1.120.81–1.55

Cardiovascular events

HR 0.470.30–0.74

Cardiovascular events

HR 0.860.64–1.16

Other lipid agentsCardiovascular eventsAll-cause mortality

Other lipid agents × cardiovascular eventshelps?settled

unlikelylikely

0.800.50 without it

Other lipid agents × all-cause mortalityhelps?one trial

unlikelylikely

0.500.50 without it

← favours treatmentfavours comparator →

this papermore certainless certain

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Association of fenofibrate therapy with cardiovascular events and mortality in diabetes patients with early-diagnosed hyperlipidemia.

What the trial testedrandomised · 3,861 people · 2026

Reduced deaths

Reduced cardiovascular events

Reduced cardiovascular events

No clear effect on deaths

Five numbers in the abstract

Where each one falls

Where it lands on the map

What it changes

Among 8 other studies

Not cited yet