ArticleKidney medicine2026
Longitudinal Changes in Left Ventricular Geometry After Kidney Transplantation and Their Implications on Cardiovascular Risk.
Article in Kidney medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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16 authors.
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Abstract
Rationale & Objective: Kidney transplantation (KT) alleviates the hemodynamic burden in chronic kidney disease on dialysis. However, cardiovascular disease remains the leading cause of death after KT. This study evaluated the metabolic and hemodynamic burden and its impact on myocardial remodeling and clinical outcomes after KT. Study Design: Multicenter observational prospective cohort study. Setting & Participants: 600 patients who underwent echocardiography before and 3 years after KT from 8 university hospitals in Korea. Predictors: Changes in metabolic parameters (glycosylated hemoglobin [HbA Outcomes: Primary outcome was major adverse cardiovascular events (MACE). Secondary outcomes included left ventricular geometry changes. Analytical Approach: Cox proportional hazards models were used to assess the association between echocardiographic changes and MACE. Results: TG and HbA Limitations: Only patients with baseline and follow-up echocardiography were included, potentially introducing selection bias. Conclusions: Hemodynamic improvements are associated with decreased left ventricular size; better metabolic control is associated with greater wall thickness improvement. RWT increases predicted MACE. Optimizing metabolic control to promote balanced left ventricular improvement could enhance cardiovascular outcomes in patients receiving KTs.
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