ArticleKidney medicine2026
Case Series of Histopathological Findings in Chronic Kidney Disease: Insights From the Kidney Precision Medicine Project.
Article in Kidney medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Shared multicellular injury programs of acute and chronic kidney disease enable mechanistic patient stratification.medRxiv : the preprint server for health sciences · 2026Article
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Authors and funding
24 authors.
Funding
Abstract
Rationale & Objective: The Kidney Precision Medicine Project is obtaining kidney biopsies from people with chronic kidney disease (CKD) and acute kidney injury for comprehensive clinical, histopathological, and molecular characterization. Here, we describe histopathological findings from a subset of kidney biopsies from adults with CKD. Study Design: Descriptive case series of histopathology findings from adjudicated CKD biopsies. Setting & Participants: Kidney Precision Medicine Project enrolled adults with CKD and diabetes (DKD) and/or hypertension (HCKD) with persistent eGFR 30-59 mL/min/1.73 m Exposures: This is a descriptive study without defined exposures. Outcomes: Characterization of glomerular, tubulointerstitial, and vascular histopathological features across CKD biopsies. Analytical Approach: Continuous variables were summarized as mean (standard deviation) or median (interquartile range); categorial variables were summarized as count (percentage). Results: Participants' mean age was 59 years, 59% were female. Mean eGFR was 55 mL/min/1.73 m Limitations: Small sample size and lack of longitudinal data limit generalizability. Conclusions: Kidney biopsies in people with common causes of CKD demonstrate a broad range of histopathology and may have clinical utility. Unsuspected disease processes and unexpected and nonspecific findings precluding a definitive diagnosis are often present.
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Registered trials
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