Evidence map›Paper›PMID 41623462›Full record

ArticleiScience2026

Anita Wagner, Juulia H Lautaoja-Kivipelto, Kalle Pehkonen, Antti Hassinen, Minna Kuusela, Lisa Röttger, Elena Herbers, Anna Ioannidou, Sophia Mädler, Ina Rothenaigner and 15 more

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Anita WagnerResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Juulia H Lautaoja-KivipeltoResearch Unit of Biomedicine and Internal Medicine, Faculty of Medicine University of Oulu, 90014 Oulu, Finland.
Kalle PehkonenResearch Unit of Biomedicine and Internal Medicine, Faculty of Medicine University of Oulu, 90014 Oulu, Finland.
Antti HassinenInstitute for Molecular Medicine Finland, FIMM, University of Helsinki, 00014 Helsinki, Finland.
Minna KuuselaResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Lisa RöttgerChair for Molecular Nutritional Medicine, Technical University of Munich, TUM School of Life Sciences Weihenstephan, 85354 Freising, Germany.
Elena HerbersResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Anna IoannidouDivision of Cardiovascular Medicine, Department of Medicine Solna, Karolinska Institutet, 17177 Stockholm, Sweden.
Sophia MädlerDepartment of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.
Ina RothenaignerResearch Unit Signaling and Translation, Helmholtz Zentrum München, 85764 Neuherberg, Germany.
Soumya SrinivasanChair for Molecular Nutritional Medicine, Technical University of Munich, TUM School of Life Sciences Weihenstephan, 85354 Freising, Germany.
Sini LaasonenResearch Unit of Biomedicine and Internal Medicine, Faculty of Medicine University of Oulu, 90014 Oulu, Finland.
M Tanvir RahmanResearch Unit of Biomedicine and Internal Medicine, Faculty of Medicine University of Oulu, 90014 Oulu, Finland.
Pinja ElomaaFolkhälsan Research Center, 00290 Helsinki, Finland.
Saija KortetjärviResearch Unit of Biomedicine and Internal Medicine, Faculty of Medicine University of Oulu, 90014 Oulu, Finland.
Anneli OlssonDivision of Cardiovascular Medicine, Department of Medicine Solna, Karolinska Institutet, 17177 Stockholm, Sweden.
Olavi UkkolaResearch Unit of Biomedicine and Internal Medicine, Faculty of Medicine University of Oulu, 90014 Oulu, Finland.
Kamyar HadianResearch Unit Signaling and Translation, Helmholtz Zentrum München, 85764 Neuherberg, Germany.
Matthias MannDepartment of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.
Hilkka PeltoniemiEira Hospital, 00150 Helsinki, Finland.
Kirsi H PietiläinenResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Martin KlingensporChair for Molecular Nutritional Medicine, Technical University of Munich, TUM School of Life Sciences Weihenstephan, 85354 Freising, Germany.
Kirsi A VirtanenTurku PET Centre, Turku University Hospital, 20520 Turku, Finland.
Carolina E HagbergDivision of Cardiovascular Medicine, Department of Medicine Solna, Karolinska Institutet, 17177 Stockholm, Sweden.
Eija PirinenResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial abnormalities drive subcutaneous white adipose tissue dysfunction in obesity, yet

Indexed as

AdipocyteHuman metabolismLipidMitochondriaObesitySpheroid

Identifiers

PMID41623462
PMCPMC12856283

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.