ArticleBioinformation2025
Longitudinal study evaluating the role of physical activity in modifying Parkinson's disease progression.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The role of physical activity in modifying Parkinson's disease progression is of interest. This longitudinal study followed 118 patients with idiopathic Parkinson's disease over 24 months to evaluate the impact of physical activity on disease progression. Participants were grouped based on physical activity levels sedentary, moderately active and highly active using standardized activity questionnaires. Disease severity was assessed using the Unified Parkinson's Disease Rating Scale (UPDRS) and Hoehn and Yahr staging. Patients with higher physical activity levels showed slower motor and functional decline compared to sedentary individuals. Thus, we show that regular physical activity may positively influence the trajectory of Parkinson's disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.