Evidence map›Paper›PMID 41624513›Full record

ArticleMaterials today. Bio2026

TZM Mo alloy behaves superb as biodegradable metal for bone-fracture healing intramedullary nail implant.

Junyu Qian, Yukun Zhou, Zhenhai Xie, Jinjing Liu, Ping Li, Wenjie Tao, Yuanhao Wang, Fei Gao, Hui Zeng, Deli Wang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Junyu QianInstitute of Biomedical Engineering, College of Medicine, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, 610031, China.
Yukun ZhouInstitute of Biomedical Engineering, College of Medicine, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, 610031, China.
Zhenhai XieInstitute of Biomedical Engineering, College of Medicine, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, 610031, China.
Jinjing LiuInstitute of Biomedical Engineering, College of Medicine, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, 610031, China.
Ping LiSchool and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction, Guangzhou Medical University, Guangzhou, China.
Wenjie TaoInstitute of Biomedical Engineering, College of Medicine, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, 610031, China.
Yuanhao WangInstitute of Biomedical Engineering, College of Medicine, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, 610031, China.
Fei GaoInstitute of Biomedical Engineering, College of Medicine, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, 610031, China.
Hui ZengDepartment of Orthopedics, Medical Innovation Technology Transformation Center of Shenzhen Second People's Hospital, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.
Deli WangNational & Local Joint Engineering Research Centre of Orthopaedic Biomaterials, Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, 518036, China.
Haotian QinNational & Local Joint Engineering Research Centre of Orthopaedic Biomaterials, Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, 518036, China.
Yingqi ChenNational & Local Joint Engineering Research Centre of Orthopaedic Biomaterials, Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, 518036, China.
Guojiang WanInstitute of Biomedical Engineering, College of Medicine, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, 610031, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone fracture repair, particularly assisted by load-bearing implants, faces tough clinical challenges, necessitating novel biomaterials that are mechanically strong, biocompatible and biodegradable to achieve effective healing. Metallic molybdenum (Mo) has shown promise in this regard, whereas little has been done with considering its alloys that are more advantageous on many aspects over its pure counterpart. Herein, we demonstrate that the TZM Mo alloy (namely Titanium-Zirconium-Molybdenum, also Mo-Ti-Zr) performed superb efficacy in the repair of rat femoral fractures with its intramedullary nails (IMNs) prototype product even as compared with pure Mo. The TZM alloy had superior mechanical strength and more uniform degradation than Mo, meeting the requirements for next-generation biodegradable IMNs. Moreover, the

Indexed as

Angiogenesis & osteogenesis couplingBiodegradable metalsBone fracture healingIntramedullary nailTZM Mo alloy

Identifiers

PMID41624513
PMCPMC12858364

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.