Evidence map›Paper›PMID 41624996›Full record

SynthesisJournal of diabetes research2026

Deciphering the Role of Sirtuin-1 Gene Polymorphism in Diabetic Nephropathy: A Systematic Review and Meta-Analysis.

Hira Moin, Munazza Asad, Maaz Waseem, Sarim Zafar, Hania Syed, Ramsha Syed, Momina Hussain

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of diabetes research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hira MoinDepartment of Physiology, NUST School of Health Sciences, National University of Sciences and Technology (NUST), H-12 Sector, Islamabad, Pakistan, nust.edu.pk.ORCID https://orcid.org/0000-0002-8793-3844
Munazza AsadDepartment of Physiology, NUST School of Health Sciences, National University of Sciences and Technology (NUST), H-12 Sector, Islamabad, Pakistan, nust.edu.pk.ORCID https://orcid.org/0009-0003-1498-3669
Maaz WaseemDepartment of Microbiology and Biotechnology, Atta-ur-Rehman School of Applied Biosciences, National University of Sciences and Technology (NUST), H-12 Sector, Islamabad, Pakistan, nust.edu.pk.ORCID https://orcid.org/0000-0003-3876-9192
Sarim ZafarDepartment of Physiology, NUST School of Health Sciences, National University of Sciences and Technology (NUST), H-12 Sector, Islamabad, Pakistan, nust.edu.pk.ORCID https://orcid.org/0009-0006-1711-6028
Hania SyedDepartment of Medicine, Al-Nafees Medical College, Isra University, Islamabad, Pakistan, isra.edu.pk.
Ramsha SyedDepartment of Surgery, Fauji Foundation Hospital, Rawalpindi, Pakistan.
Momina HussainChinese Academy of Tropical Agricultural Sciences, Sanya, China, catas.cn.ORCID https://orcid.org/0000-0002-5017-3976

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sirtuin-1-gene (

Indexed as

Diabetic NephropathiesGenetic Predisposition to DiseasePolymorphism, Single NucleotideSirtuin 1HumansSIRT1 protein, humanSirtuin 1diabetic nephropathygenetic susceptibilitymeta-analysispolymorphismrenal diseaserisk stratificationsirtuin-1

Identifiers

PMID41624996
PMCPMC12853138

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.