ArticleMaterials today. Bio2025
Copper-incorporated hydrogels loaded with curcumin microspheres for the repair of bone defects.
Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- High-performance hydrogels in orthopedics: Structural design, performance tuning, and clinical potential.Materials today. Bio · 2026Review
- Curcumin-based smart responsive hydrogels: A controlled release system for bone defect regeneration.Regenerative therapy · 2026Review
- Bifunctional 3D-printed PEEK scaffolds incorporating hydrogel-encapsulated magnesium-quinone nanosheets for antibacterial activity and mandibular bone regeneration.Materials today. Bio · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Addressing bone defects continues to be an exceedingly difficult challenge owing to local immune dysregulation, vascular injury, and disorders of osteogenesis. No entirely satisfactory resolution has been achieved. In this work, through loading curcumin/poly (lactic-co-glycolic acid) microspheres constructed via a double emulsion technique, a copper-incorporated carboxymethyl chitosan/sodium alginate hydrogel (CA-Cur@Cu hydrogel) was developed. The CA-Cur@Cu hydrogels can sustain the release of curcumin for a long time. This sustained release demonstrates effective antioxidant and anti-inflammatory properties, inducing M2 polarization of macrophages and enhancing the bone immune microenvironment. Furthermore, Cu
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