Evidence map›Paper›PMID 41625616›Full record

ReviewFrontiers in psychiatry2025

Pediatric obsessive-compulsive disorder as a developmental disorder of cognitive-emotional control: a transdiagnostic and family-integrated perspective.

Cristina Di Vincenzo, Francesco Demaria, Ilaria Bertoncini, Deny Menghini, Alessandro Antonietti, Stefano Vicari, Maria Pontillo

Abstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cristina Di VincenzoDepartment of Psychology, Catholic University of Sacred Hearth, Milan, Italy.
Francesco DemariaChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico/Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy.
Ilaria BertonciniChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico/Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy.
Deny MenghiniChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico/Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy.
Alessandro AntoniettiDepartment of Psychology, Catholic University of Sacred Hearth, Milan, Italy.
Stefano VicariChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico/Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy.
Maria PontilloChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico/Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric obsessive-compulsive disorder (OCD) is a complex condition that typically emerges in childhood or adolescence and is closely linked to developmental changes in cognitive and emotional control. This mini-review offers a clinically oriented synthesis of pediatric OCD from a developmental and transdiagnostic perspective, framing it as a disturbance of flexibility, inhibition, and distress regulation that organizes its clinical presentation. Variations in these control processes across development shape the content and form of obsessive-compulsive symptoms and contribute to their frequent overlap with conditions such as autism spectrum disorder, tic disorders and Tourettic OCD, ADHD, bipolar disorder, and psychosis-risk presentations, which share similar regulatory vulnerabilities. Within this framework, family accommodation is conceptualized as an interpersonal extension of the child's regulatory difficulties, temporarily reducing distress while reinforcing reliance on external control. A transdiagnostic focus on underlying regulatory mechanisms also helps to clarify why interventions such as developmentally adapted cognitive-behavioral therapy with exposure and response prevention, family-focused treatments, and process-based transdiagnostic protocols can promote more flexible cognitive-emotional regulation in both the child and the family system. Taken together, these elements support a developmental, family-integrated, and transdiagnostic conceptualization of pediatric OCD centered on cognitive-emotional control.

Indexed as

cognitive–emotional controlfamily accommodationobsessive–compulsive disorderpediatric OCDtransdiagnostic approach

Identifiers

PMID41625616
PMCPMC12856497

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.