SynthesisFrontiers in neurology2025
Effects of general anesthesia on short-term outcomes of patients with acute ischemic stroke after endovascular treatments: a meta-analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
The optimal anesthetic strategy for endovascular treatment (EVT) in acute ischemic stroke (AIS) remains uncertain. This meta-analysis of randomized controlled trials (RCTs) compared the effects of general anesthesia (GA) and non-general anesthesia (non-GA) on reperfusion success and clinical outcomes after EVT. A systematic search of PubMed, Embase, Web of Science, and the Cochrane Library was performed. Eligible RCTs compared GA versus non-GA in adults with AIS undergoing EVT. The primary outcome was successful angiographic reperfusion (modified Thrombolysis in Cerebral Infarction 2b-3). Secondary outcomes included functional independence (modified Rankin Scale 0-2) and all-cause mortality at 3 months. Risk ratios (RRs) with 95% confidence intervals (CIs) were pooled using a random-effects model accounting for the influence of potential heterogeneity. Eleven RCTs encompassing 1,674 patients were included. Compared with non-GA, GA significantly increased the likelihood of successful reperfusion (RR = 1.08, 95% CI 1.02-1.13; I Systematic review registration: https://www.crd.york.ac.uk/prospero/search, identifier CRD420251169607.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.