ArticleHRB open research2025
Predictors of Recent Incidence Trends in Sexually Transmitted Infections: A Systematic Review Protocol.
Article in HRB open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Detection of Genital Pathogens and Co-Infections by Multiplex RT-qPCR: Associations with HIV Positivity and Demographic Factors.Diagnostics (Basel, Switzerland) · 2026Article
- Predictors of Recent Incidence Trends in Sexually Transmitted Infections: A Systematic Review Protocol.HRB open research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Sexually transmitted infections (STIs) are a major global health concern, with millions of new cases occurring annually, particularly among young adults. These infections can lead to serious health complications, including infertility and increased risk of HIV, and are compounded by social stigma and mental health challenges. There have been significant global increases in STI diagnoses in recent years. The objective of this systematic review is to synthesise evidence on the predictors of trends in gonorrhoea, chlamydia, syphilis, and HIV over the last ten years. We aim to provide insight into the multifaceted drivers of the recent increasing STI diagnosis rates. Methods: We have developed a comprehensive search strategy that includes searching for relevant published literature and grey literature. We will include studies that contain evidence of longitudinal associations between changes in the incidence of diagnoses of four targeted STIs (i.e., gonorrhoea, chlamydia, syphilis, and HIV) during the last ten years. In addition, we will explore changes in sociodemographic and behavioural variables during the same time among representative samples of national populations. We will conduct a narrative analysis of the included studies. Discussion: The proposed synthesis plan is part of a larger research project that has been designed in response to the priorities of sexual health policymakers in Ireland. It will provide useful information regarding recent international trends in diagnoses of gonorrhoea, chlamydia, syphilis, and HIV, which will inform further efforts to understand the recent increases in STI diagnoses in Ireland. We acknowledge that it will be limited by publication bias, the biases affecting the included studies, a potential lack of data on important sub-populations, and restrictions related to testing availability across countries. Ultimately, trends in STI diagnoses are best understood through the design of comprehensive behavioural surveillance systems, which this review may usefully inform.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.