SynthesisFrontiers in oncology2025
Prevalence and risk factors for postoperative ileus in colorectal cancer patients: a systematic review and meta-analysis.
Synthesis in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Tegileridine versus Sufentanil Patient-Controlled Intravenous Analgesia for Gastrointestinal Recovery in Elderly Patients Undergoing Laparoscopic Colorectal Cancer Surgery: A Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
- The Multidisciplinary Approach to Enhanced Recovery After Surgery in Colorectal Cancer: An Updated Narrative Review.Cureus · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Postoperative ileus (POI) is a common complication following colorectal cancer surgery, with its incidence and risk factors remaining controversial. This study aims to investigate the overall prevalence of POI in colorectal cancer patients and its risk factors through a meta-analysis. Methods: A systematic search was conducted in the Web of Science, Cochrane Library, PubMed, and Embase databases from their inception to August 7, 2025. Two researchers independently screened studies, extracted data, and assessed the risk of bias in the included studies. Statistical analysis was performed using Stata 15.1. Results: Thirty studies involving 73,433 patients were included, with 7,463 cases of POI. The overall Prevalence of POI in colorectal cancer patients was [ES = 9%, 95% CI: 8%-11%]. Meta-analysis showed that male [OR = 2.20, 95% CI: 1.76-2.76], operative time >3 hours [OR = 1.75, 95% CI: 1.20-2.40], open surgery [OR = 2.95, 95% CI: 2.20-3.95], ileostomy [OR = 4.78, 95% CI: 2.30-9.94], previous abdominal surgery [OR = 2.21, 95% CI: 1.75-2.79], and age≥65 years [OR = 1.04, 95% CI: 1.01-1.06] may be potential risk factors for POI in colorectal cancer patients. The included studies were of high quality, and no significant publication bias was detected. Conclusion: Based on existing evidence, male, operative time >3 hours, open surgery, ileostomy, previous abdominal surgery, and age≥65 years may be potential risk factors for POI in colorectal cancer patients. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD420251121761.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.