Evidence map›Paper›PMID 41626537›Full record

ArticleJournal of nutritional science2026

Dietary magnesium intake and dementia risk in community-dwelling people aged 40-74 years: an 8-year cohort study.

Irina Bulycheva, Yumi Watanabe, Kaori Kitamura, Keiko Kabasawa, Toshiko Saito, Akemi Takahashi, Ryosaku Kobayashi, Rieko Oshiki, Ribeka Takachi, Shoichiro Tsugane and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nutritional science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Irina BulychevaDivision of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.ORCID https://orcid.org/0000-0001-7289-3037
Yumi WatanabeDivision of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Kaori KitamuraDivision of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Keiko KabasawaDepartment of Health Promotion Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.ORCID https://orcid.org/0000-0002-3665-9996
Toshiko SaitoDivision of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Akemi TakahashiDepartment of Rehabilitation, Niigata University of Rehabilitation, Niigata, Japan.
Ryosaku KobayashiDepartment of Rehabilitation, Niigata University of Rehabilitation, Niigata, Japan.
Rieko OshikiDepartment of Rehabilitation, Niigata University of Rehabilitation, Niigata, Japan.
Ribeka TakachiDepartment of Food Science and Nutrition, Nara Women's University Graduate School of Humanities and Sciences, Nara, Japan.
Shoichiro TsuganeInternational University of Health and Welfare Graduate School of Public Health, Tokyo, Japan.
Osamu YamazakiNiigata Prefectural Government, Niigata, Japan.
Kei WatanabeDivision of Orthopedic Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Kazutoshi NakamuraDivision of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.ORCID https://orcid.org/0000-0002-8618-7632

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary magnesium (Mg) is a potentially modifiable factor in preventing dementia, but current evidence supporting this remains insufficient and inconclusive. This study aimed to determine whether dietary Mg is associated with the risk of dementia among middle-aged and older people. Participants of this 8-year cohort study were 13,032 community-dwelling individuals aged 40-74 years. Dietary data were collected using a validated food frequency questionnaire in 2011-2013. Mg intake was adjusted for energy intake using the residual method. The outcome was newly diagnosed dementia determined using Japan's long-term care insurance database. Covariates included demographic characteristics, body size, lifestyles, and disease histories. Cox proportional hazard models were used to determine adjusted hazard ratios (HRs). The mean age of participants was 59.0 years. Dementia occurred in 148 males and 138 females. Lower quartiles of energy-adjusted Mg intake were associated with a higher risk of dementia (

Indexed as

DementiaDietMagnesiumAdultAgedAging in PlaceCohort StudiesFemaleHumansIndependent LivingJapanMaleMiddle AgedProportional Hazards ModelsRisk FactorsMagnesiumAD, Alzheimer’s diseaseAlzheimer’s diseaseBMI, body mass indexCohort studyDementiaDietFFQ, food frequency questionnaireHR, hazard ratioIL, interleukinLTCI, long-term care insuranceMagnesiumMET, metabolic equivalentMg, magnesiumNMDA, N-methyl D-aspartatePA, physical activityTNF-α, tumor necrosis factor-α

Identifiers

PMID41626537
PMCPMC12854930

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.