Evidence map›Paper›PMID 41626679›Full record

ReviewCurrent pharmaceutical biotechnology2025

Potential Pathogens Associated with Colorectal Cancer.

Javad Nezhadi, Hossein Samadi Kafil, Farshad Mahdavi, Mohammad Sadrkabir, Shahryar Hashemzadeh, Seyed Yaghoub Moaddab, Roghayeh Nouri, Yalda Mohammadzadeh-Asl, Simin Sattarpour, Mohammad Ahangarzadeh Rezaee

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pharmaceutical biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Javad NezhadiStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Hossein Samadi KafilDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Farshad MahdaviDepartment of General Surgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad SadrkabirDepartment of Internal Medicine, Islamic Azad University, Tabriz Branch, Tabriz, Iran.
Shahryar HashemzadehDepartment of General Surgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Seyed Yaghoub MoaddabLiver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Roghayeh NouriDepartment of Microbiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Yalda Mohammadzadeh-AslDepartment of Microbiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Simin SattarpourDepartment of Basic Sciences, Faculty of Allied Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad Ahangarzadeh RezaeeInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Funding

Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran 70792
6 · The paper itself

Abstract

Colorectal Cancer (CRC) is a malignancy in which the cells of the colon and rectum grow uncontrollably. This disease initially appears as an adenomatous polyp, which, over time, turns into an advanced adenoma with high-grade dysplasia and becomes the basis of invasive cancer. Dysbiosis refers to the reduction of microbial diversity and disruption of the balance in the population of beneficial (microbiota) and harmful (pathogenic) microorganisms. The disruption of the balance causes an increase in pathogenic microbial species, which play a role in creating a pro-inflammatory environment. Therefore, dysbiosis can disrupt the balance of the microbiota population, leading to Gastrointestinal (GI) disorders like cancer. According to research, it has been established that certain pathogenic bacteria, specifically

Indexed as

BacteriaColorectal NeoplasmsDysbiosisGastrointestinal MicrobiomeAnimalsHumanscarcinogenesis.Colorectal cancerdysbiosismicrobiotapathogenic bacteriapro-inflammatory environment

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.