EMS-induced mutagenesis of Aspergillus terreus for enhanced xylanase production and subsequent biotransformation of sugarcane bagasse-derived xylose towards xylitol.

Satwika Das, Ramandeep Kaur, Naveen Kumar Bhukya, Kanimozhi Jeyaram, Ashish A Prabhu

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Article in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Satwika DasBioprocess Development Laboratory, Department of Biotechnology, National Institute of Technology Warangal, Hanamkonda, Warangal, 506004, Telangana, India.

Ramandeep KaurBioprocess Development Laboratory, Department of Biotechnology, National Institute of Technology Warangal, Hanamkonda, Warangal, 506004, Telangana, India.

Naveen Kumar BhukyaBioprocess Development Laboratory, Department of Biotechnology, National Institute of Technology Warangal, Hanamkonda, Warangal, 506004, Telangana, India.

Kanimozhi JeyaramDepartment of Biotechnology, Kalasalingam Academy of Research and Education, Krishnankoil, Virudhunagar (Dt), 626126, Tamil Nadu, India.

Ashish A PrabhuBioprocess Development Laboratory, Department of Biotechnology, National Institute of Technology Warangal, Hanamkonda, Warangal, 506004, Telangana, India. ashishp@nitw.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Agro-industrial wastes contain lignocellulose, of which, the hemicellulosic fraction can be utilized for the production of value-added products such as xylitol, leading to the generation of a cost-effective and sustainable bioprocess. Biomass pretreatment is necessary for efficient enzymatic hydrolysis, with alkaline pretreatment enhancing the bioavailability of fermentable sugars such as xylose from the hemicellulosic component of lignocellulosic biomass. In the current study, a xylanolytic Aspergillus terreus strain was exposed to the chemical mutagen EMS in an attempt to enhance the xylanase enzyme production, reaching 12.83 UmL⁻¹. Subsequently, upon optimization of process and parameters, at a pH of 6.5, a reaction temperature of 60 °C, with the presence of 20 mM Zn

Indexed as

AspergillusCelluloseEndo-1,4-beta XylanasesMutagenesisSaccharumXylitolXyloseBiotransformationFermentationHydrogen-Ion ConcentrationMutagensYarrowiabagasseCelluloseEndo-1,4-beta XylanasesMutagensXylitolXyloseAspergillus terreusChemical mutagenesisLignocellulosic biomassXylanolytic activityXylitol

Identifiers

PMID41627447

DOI10.1186/s12934-022-01997-w

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.