ArticleProceedings of the National Academy of Sciences of the United States of America2026
Selective peroxynitrite-mediated protein nitration catalyzed by glyoxalase domain containing protein 4.
Sarah Wright, Vu C Dang, Sami Hussain, Prasanna Kandel, Robert P Brendza, Sahar Mazhar, Marie Whitmore, Selim Boudoukha, Jaskamaljot Kaur Banwait, Robert Van Der Linden and 12 more
Abstract read
In one paragraphArticle in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
22 authors.
Sarah WrightNitrase Therapeutics, Brisbane, CA 94005.
Vu C DangNitrase Therapeutics, Brisbane, CA 94005.
Sami HussainNitrase Therapeutics, Brisbane, CA 94005.
Prasanna KandelNitrase Therapeutics, Brisbane, CA 94005.
Robert P BrendzaNitrase Therapeutics, Brisbane, CA 94005.
Marie WhitmoreNitrase Therapeutics, Brisbane, CA 94005.
Selim BoudoukhaNitrase Therapeutics, Brisbane, CA 94005.
Jaskamaljot Kaur BanwaitDepartment of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294.ORCID 0009-0005-7494-1588 Edward VertudesNitrase Therapeutics, Brisbane, CA 94005.
Kate MarkhamNitrase Therapeutics, Brisbane, CA 94005.
Grace PohanNitrase Therapeutics, Brisbane, CA 94005.
Andy JenningsNitrase Therapeutics, Brisbane, CA 94005.
Sheerin Shahidi-LathamNitrase Therapeutics, Brisbane, CA 94005.
Frank KayserNitrase Therapeutics, Brisbane, CA 94005.
Aaron L LuciusDepartment of Chemistry, The University of Alabama at Birmingham, Birmingham, AL 35294.ORCID 0000-0001-8636-5411 Arun KashyapNitrase Therapeutics, Brisbane, CA 94005.
Harry IschiropoulosChildren's Hospital of Philadelphia Research Institute and University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0001-8284-5098 Funding
Gisela and Dennis Alter Endowed Chair in Pediatric Neonatology and Stoke Investigator Funds N/AMichael J. Fox Foundation for Parkinson's Research (MJFF) MJFF-008730
6 · The paper itselfAbstract
Tyrosine nitration alters the structure, function, and cellular localization of proteins and is implicated in the pathology of multiple diseases [G. Ferrer-Sueta
Indexed as
alpha-SynucleinNeoplasm ProteinsParkinson Disease, SecondaryPeroxynitrous AcidTyrosineAnimalsBiocatalysisCell Line, TumorCorpus StriatumDisease Models, AnimalFemalegamma-SynucleinGene Knockdown TechniquesHumansMaleMethamphetaminealpha-Synucleingamma-SynucleinGLOD4 protein, humanMethamphetamineNeoplasm ProteinsPeroxynitrous AcidTyrosine3-nitrotyrosinealpha-synucleinglyoxalase domain containing protein 4 (GLOD4)nitrasestyrosine nitration
Identifiers
PMID41628334
PMCPMC12890929
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390