Evidence map›Paper›PMID 41628974›Full record

ArticleSaudi medical journal2026

Influence of Metabolic Dysfunction-Associated Steatotic Liver Disease on Pattern and Management of Acute Coronary Syndrome.

Elshazly Abdulkhalik, Nagat Ibrahim, Selim Sidhom, Hesham H Alqurashi, Khaled Alghashmari, Muhammad Alotaibi, Ahmed Alqurashi, Moath Alzahrani, Shahad Alqahtani, Abdulaziz Alshalan and 4 more

Abstract read
In one paragraph

Article in Saudi medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elshazly AbdulkhalikDepartment of Cardiology, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Nagat IbrahimDepartment of Gastroenterology, Hepatology, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Selim SidhomDepartment of Cardiology, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Hesham H AlqurashiDepartment of Gastroenterology, Hepatology, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Khaled AlghashmariDepartment of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Muhammad AlotaibiDepartment of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Ahmed AlqurashiDepartment of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Moath AlzahraniDepartment of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Shahad AlqahtaniDepartment of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Abdulaziz AlshalanDepartment of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Nouran AlthumaliDepartment of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Mazen AljohaniDepartment of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Saud AlzahraniDepartment of Internal Medicine, King Abdulaziz Specialist Hospital, Taif, Makkah Province, Saudi Arabia.
Haidi Karam-Allah RamadanDepartment of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assiut University, Assiut, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the influence of metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and hepatic fibrosis on the pattern and management of patients who had acute coronary syndrome (ACS).

methodsRetrospective records of patients with ACS included demographic, electrocardiographic, and laboratory data of platelets count, glycated hemoglobin, lipogram, liver and cardiac enzymes. Ultrasound was used to evaluate fatty liver. Coronary angiography data included the number, site and percentage of the coronary arteries occluded. The type and outcome of treatment of ACS were recorded. Laboratory markers were measured to evaluate fibrosis.

resultsThe study recruited 259 patients, and the majority were males. MASLD was detected in 123 (47.5%). The ST segment-elevation myocardial infarction (STEMI) was reported in 42.9% and non-STEMI (NSTEMI) in 30.1%. MASLD patients had frequent STEMI (38.2%) and NSTEMI (31.7%) with more involvement of left main coronary artery (10.6%). Patients with MASLD and higher fibrosis showed involvement of multiple coronary arteries and needed revascularization but without significant difference from non-MASLD. Left anterior descending and right coronary arteries were significantly involved in higher fibrosis.

conclusionSTEMI and NSTEMI were frequent in MASLD. People with MASLD and hepatic fibrosis had more incidence of occlusion of multiple coronary arteries and needed cardiac intervention.

Indexed as

Acute Coronary SyndromeFatty LiverLiver CirrhosisAgedCoronary AngiographyElectrocardiographyFemaleHumansMaleMiddle AgedRetrospective StudiesST Elevation Myocardial InfarctionAcute coronary syndromeAngiographyCoronary arteryFatty liverHepatic fibrosisMASLDMyocardial infarctionSteatosis

Identifiers

PMID41628974
PMCPMC12862591

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.