Evidence map›Paper›PMID 41629635›Full record

SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026

Unmasking the cognitive burden of adult tuberculous meningitis: A systematic review and meta analysis.

Sanchit Shailendra Chouksey, Akansha Jain, Varun Kumar Singh, Rameshwar Nath Chaurasia, Abhishek Pathak, Shahnawaz Ahmad, Pranjal Kumar Singh, Deepika Joshi, Vijay Nath Mishra, Anand Kumar

Abstract readSystematic ReviewMeta-AnalysisReview
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In one paragraph

Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sanchit Shailendra ChoukseyDepartment of Neurology, Datta Meghe Medical College, Nagpur (DMIHER-DU), Nagpur, 440016, India.
Akansha JainDepartment of Neurology, Institute of Medical Science, Banaras Hindu University, Varanasi, 221005, India.
Varun Kumar SinghDepartment of Neurology, Institute of Medical Science, Banaras Hindu University, Varanasi, 221005, India.
Rameshwar Nath ChaurasiaDepartment of Neurology, Institute of Medical Science, Banaras Hindu University, Varanasi, 221005, India. goforrameshwar@gmail.com.ORCID http://orcid.org/0000-0002-5697-8804
Abhishek PathakInstitute of Medical Science, Banaras Hindu University, Varanasi, 221005, India.
Shahnawaz AhmadDepartment of Neurology, Institute of Medical Science, Banaras Hindu University, Varanasi, 221005, India.
Pranjal Kumar SinghKirori Mal College, University of Delhi, New Delhi, 110007 , India.
Deepika JoshiDepartment of Neurology, Institute of Medical Science, Banaras Hindu University, Varanasi, 221005, India.
Vijay Nath MishraDepartment of Neurology, Institute of Medical Science, Banaras Hindu University, Varanasi, 221005, India.
Anand KumarDepartment of Neurology, Institute of Medical Science, Banaras Hindu University, Varanasi, 221005, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTuberculous meningitis (TBM) is a devastating form of extrapulmonary tuberculosis with high mortality and substantial long-term neurological sequelae. Cognitive impairment is a particularly debilitating outcome yet remains under-recognised and understudied. However, heterogeneous methodologies and tools remain a major barrier to pooling data and forming clinical guidelines. AIMS AND

objectivesTo evaluate the prevalence, patterns, and determinants of cognitive impairment among adult TBM patients. METHODOLOGY: A total of 761 records were identified, and six studies met the inclusion criteria and were included in the qualitative synthesis, of which four studies were included in the quantitative meta-analysis.

resultsCognitive impairment ranging from 12% to over 90% was found across studies, with severity ranging from mild deficits to severe global dysfunction. The most consistently affected domains were memory, attention, and executive function, followed by language and visuospatial.

conclusionMultidomain cognitive impairment is a common sequela of tuberculous meningitis, underscoring the need for routine screening and long-term rehabilitation.

Indexed as

Cognitive DysfunctionTuberculosis, MeningealHumansClinical outcomesCognitive impairmentInfectious diseasesTuberculous meningitis

Identifiers

PMID41629635

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.