Evidence map›Paper›PMID 41629793›Full record

ArticleBMC geriatrics2026

Frailty in older patients with atrial fibrillation in Vietnam: a comparison between the physical frailty phenotype and the Clinical Frailty Scale.

Tan Van Nguyen, Huy Quoc Nguyen, Lilin Chen, Mark Woodward, Tu Ngoc Nguyen

Abstract readComparative Study
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Tan Van NguyenDepartment of Geriatrics and Gerontology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Huy Quoc NguyenDepartment of Geriatrics and Gerontology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Lilin ChenSchool of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.
Mark WoodwardThe George Institute for Global Health, School of Public Health, Imperial College London, London, United Kingdom.
Tu Ngoc NguyenThe George Institute for Global Health, Sydney, New South Wales, Australia. tunguyen@georgeinstitute.org.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is limited evidence on the prevalence of frailty and its impact on health outcomes in older adults with atrial fibrillation (AF) in Vietnam. This study aimed to (1) Compare the agreement of the physical frailty phenotype (Fried’s criteria) and the Clinical Frailty Scale (CFS) in identifying frailty in older adults with AF, and (2) Compare the associations of these frailty definitions with hospitalisation.

methodsAdults aged 65 or older with AF attending the outpatient clinics of a hospital in Vietnam. Frailty was defined as having ≥ 3/5 of Fried’s criteria or a CFS ≥ 4. All participants were followed up for 9 months, recording hospitalisations. The kappa statistic was used to quantify the agreement between frailty defined by the modified physical frailty phenotype and the CFS. Logistic regression was applied to examine the association between frailty and hospitalisation.

resultsThere were 305 participants. They had a mean age of 76.7 (SD 7.8), 40% were female. The prevalence of frailty was 34% according to the modified physical frailty phenotype criteria, and 88% according to the CFS (kappa coefficient 0.14, 95%CI 0.09–0.19). The hospitalisation rate during follow up was 28.8%, higher in frail participants compared to the non-frail. Frailty defined as CFS ≥ 4 was significantly associated with increased hospitalisation (adjusted OR 3.72, 95%CI 1.23–11.31, p = 0.020). A non-significant association was observed with frailty defined by the modified physical frailty phenotype (adjusted OR 1.64, 95%CI 0.95–2.84, p = 0.077). Similar results were obtained when frailty was analysed as a continuous score: adjusted ORs 1.39 (95%CI 1.05–1.83, p = 0.022) for each higher category of the CFS, and 1.24 (95%CI 1.00–1.53, p = 0.051) for each unit higher of of the physical frailty score.

conclusionFrailty was highly prevalent among older patients with AF. There was a poor agreement between the two frailty criteria when identifying frail and non-frail participants in the cohort using the cut-offs. The CFS had a stronger association with hospitalisations than the modified physical frailty phenotype criteria. Further studies are needed to compare the predictive values of these two frailty definitions in older adults in Vietnam.

Indexed as

Atrial FibrillationFrail ElderlyFrailtyGeriatric AssessmentPhenotypeAgedAged, 80 and overFemaleFollow-Up StudiesHospitalizationHumansMaleVietnamAtrial fibrillationClinical Frailty ScaleFrailtyFrailty phenotypeGeriatric cardiologyVietnam

Identifiers

PMID41629793
PMCPMC13069704

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.