Evidence map›Paper›PMID 41629869›Full record

ArticleBMC surgery2026

Risk factors for transient hypoparathyroidism and hypocalcemia following total thyroidectomy with central lymph node dissection for papillary thyroid carcinoma: a single-center retrospective study.

Shuang Dong, Zhihong Chen, Chunyan Shui, Tong Liu, Yuqiu Zhou, Yongjin Li, Yongcong Cai, Chao Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shuang DongDepartment of Head and Neck Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Zhihong ChenDepartment of Head and Neck Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Chunyan ShuiDepartment of Head and Neck Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Tong LiuDepartment of Head and Neck Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Yuqiu ZhouDepartment of Head and Neck Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Yongjin LiDepartment of Head and Neck Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Yongcong CaiDepartment of Head and Neck Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.
Chao LiDepartment of Head and Neck Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China. lichao@scszlyy.org.cn.

Funding

Key Projects of Clinical Research Program of Sichuan Provincial Health Commission 24LCYJZD06
6 · The paper itself

Abstract

objectiveHypoparathyroidism and hypocalcemia are common complications following total thyroidectomy (TT). This study aimed to evaluate the risk of post-total thyroidectomy transient hypoparathyroidism and hypocalcemia through a large single-center retrospective analysis.

methodsIn this retrospective study, consecutive patients underwent total thyroidectomy from May 2021 to September 2022 were included. Postoperative parathyroid hormone (PTH) level and serum calcium levels were evaluated within 24 h. Univariate and multivariate analysis were performed for assessing risk factors for developing transient hypoparathyroidism and hypocalcemia after total thyroidectomy.

resultsA total of 1065 patients undergoing total thyroidectomy who met the inclusion criteria were enrolled in this study. Among the patients, 460 patients (43.2%) developed hypoparathyroidism after surgery, and a total 325 patients (30.5%) developed hypocalcemia. After multivariate analysis, the independent risk factors related to hypoparathyroidism are female (OR = 1.65, p < 0.001), inadvertent parathyroidectomy (OR = 2.26, p = 0.004), non-papillary thyroid microcarcinoma (OR = 1.55, p = 0.003) and capsule invasion (OR = 1.39, p = 0.034). Meanwhile, the independent risk factors related to hypocalcemia are female (OR = 1.94, p < 0.001) and inadvertent parathyroidectomy (OR = 2.01, p = 0.011).

conclusionTransient hypoparathyroidism and hypocalcemia are relatively common complications following total thyroidectomy. Female, inadvertent parathyroid gland excision, papillary thyroid microcarcinoma, and capsular invasion were identified as independent risk factors for hypoparathyroidism and hypocalcemia.

Indexed as

HypocalcemiaHypoparathyroidismLymph Node ExcisionPostoperative ComplicationsThyroid Cancer, PapillaryThyroidectomyThyroid NeoplasmsAdultFemaleHumansMaleMiddle AgedParathyroid HormoneRetrospective StudiesRisk FactorsParathyroid HormonehypocalcemiaHypoparathyroidismtotal thyroidectomy

Identifiers

PMID41629869
PMCPMC12954966

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.