Evidence map›Paper›PMID 41629975›Full record

ArticleSystematic reviews2026

Nursing interventions for patients in last days of life and their family caregivers at home: a protocol for a mixed methods systematic review.

Milene Isabel Costa Mendonça Lima, Maria da Graça Melo E Silva, Sara Maria Oliveira Pinto

Abstract read
In one paragraph

Article in Systematic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Milene Isabel Costa Mendonça LimaNursing School of Lisbon/Lisbon University, Avenida Prof Egas Moniz 1600-190, Lisbon, Portugal. mlima@campus.esel.pt.ORCID 0000-0001-9999-7290
Maria da Graça Melo E SilvaNursing Research, Innovation and Development Centre of Lisbon (CIDNUR), Nursing School of Lisbon/Lisbon University, Avenida Prof Egas Moniz 1600-190, Lisbon, Portugal.ORCID 0000-0002-0525-1824
Sara Maria Oliveira PintoRISE-Health, Nursing School of Porto, Rua Dr. António Bernardino de Almeida 830/844/856, 4200-072, Porto, Portugal.ORCID 0000-0001-9327-5270

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe demand for end-of-life care will rise significantly in coming decades due to increasing life expectancy and the growing burden of chronic diseases. Palliative care aims to support patients' preferences to remain at home (both for ongoing care and, when possible, to die). The feasibility of dying at home is shaped by a complex interplay of patient factors, the capacity of family caregivers, and the availability of home care teams and community resources. Healthcare professionals, especially nurses, are pivotal in accommodating patient preferences, and are uniquely positioned to influence the quality and feasibility of end-of-life care. A deeper understanding of their specific interventions, particularly for patients in their last days and their families, is essential to inform practice, education, and policy. This review aims to synthesise the available evidence, identify effective nursing interventions, highlight knowledge gaps and inform nursing practice, education and policy at an international level.

methodsThis mixed-methods systematic review will be conducted according to the updated methodology of the Joanna Briggs Institute and reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The search will be conducted in PsycINFO, MEDLINE, CINAHL ULTIMATE, Web of Science and Mediclatina, with no date or language restrictions. Two reviewers will independently screen data, assess methodological quality using appropriate appraisal tools, and extract data using standardized forms. Quantitative and qualitative findings will be integrated through a convergent approach. DISCUSSION: Nursing interventions in the last days of life are complex and multifaceted, critically influencing patient's comfort, dignity and quality of life, as well family experience. However, accurately identifying and defining is challenging due to variability in terminology and conceptual boundaries, particularly in studies that focus on the "last days of life". This variability may limit comparability across studies and highlight the need for greater conceptual clarity to guide research, practice, and policy.

trial registrationSystematic review registration: PROSPERO CRD420251112044.

Indexed as

CaregiversHome Care ServicesPalliative CareTerminal CareHumansSystematic Reviews as TopicCaregiversHome nursingNursingPalliative careSystematic reviewTerminal careTerminally ill

Identifiers

PMID41629975
PMCPMC12866197

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.