Evidence map›Paper›PMID 41633323›Full record

ArticleJournal of Korean medical science2026

Trends in Sedative-Hypnotic Prescription Among Insomnia Patients: A Nationwide Cohort Study From 2010 to 2022 in Korea.

Jiyoon Shin, So Yon Jun, Donghyun Won, Minah Kim, Su Young Lee, Mincheol Seo, Aesun Shin, Yu Jin Lee

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jiyoon Shin *Department of Psychiatry and Center for Sleep and Chronobiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0510-993X
So Yon Jun *Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0002-4310-3459
Donghyun WonDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0008-1832-4210
Minah KimDepartment of Psychiatry and Center for Sleep and Chronobiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0006-9278-0279
Su Young LeeDepartment of Psychiatry, Yonsei Forest Mental Health Clinic, Seoul, Korea.ORCID https://orcid.org/0000-0003-3125-3409
Mincheol SeoDepartment of Psychiatry and Center for Sleep and Chronobiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8889-9473
Aesun ShinDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6426-1969
Yu Jin LeeDepartment of Psychiatry and Center for Sleep and Chronobiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea. ewpsyche@snu.ac.kr.ORCID https://orcid.org/0000-0001-5195-2579

Funding

National Research Foundation of Korea RS-2023-00242754
6 · The paper itself

Abstract

backgroundGlobal insomnia prevalence increased during the coronavirus disease 2019 (COVID-19) pandemic, driving higher demand for sedative-hypnotics. The objective of this study was to compare sedative-hypnotic prescription patterns in South Korea from 2010 to 2022 and assess the potential impact of the COVID-19 pandemic.

methodsThis population-based cohort study from January 1, 2010, to December 31, 2022, used the Korean National Health Insurance's Health Insurance Sharing Service database of 8,136,437 (60.4% female) unique insomnia patients aged 18 and older. Prescriptions for sedative-hypnotic groups (benzodiazepines, non-benzodiazepines, antidepressants, and antipsychotics), number of patients prescribed sedative-hypnotics, and predicted and observed prescription rates by sex, age, and sedative-hypnotic group were analyzed.

resultsThe number of prescriptions per 1,000 population increased across all sedative-hypnotic groups before and during the pandemic. Women and the elderly had higher prescriptions for all sedative-hypnotic groups compared to men and other age groups. Antidepressant prescriptions saw the highest percentage increase (men 38.6%; women 37.1%) in 1st half of 2020 compared to 2019, followed by antipsychotics (men 28.9%; women 25.7%). Antidepressant prescriptions showed the largest increase relative to predicted levels across all age groups from 2020 to 2021, while non-benzodiazepines exhibited the smallest increase (men 5.6%; women 4.5%). In the 18-29 age group, prescriptions for all sedative-hypnotic groups exceeded predicted numbers in 2021.

conclusionThis study found that sedative-hypnotic prescriptions steadily increased from 2010 to 2022, with the trend becoming more pronounced during the COVID-19 pandemic, when prescription rates tended to exceed predicted levels in Korea. Monitoring the use of sedative-hypnotics for insomnia in women, the elderly, and young adults is essential for potential adverse effects and associated mental problems.

Indexed as

COVID-19Drug PrescriptionsHypnotics and SedativesPractice Patterns, Physicians'Sleep Initiation and Maintenance DisordersAdolescentAdultAgedAged, 80 and overAntidepressive AgentsAntipsychotic AgentsBenzodiazepinesCohort StudiesFemaleHumansMaleAntidepressive AgentsAntipsychotic AgentsBenzodiazepinesHypnotics and SedativesBenzodiazepinesCOVID-19 PandemicInsomniaKoreaNon-BenzodiazepinesPrescriptionSedative-Hypnotics

Identifiers

PMID41633323
PMCPMC12865212

What Socratic holds

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.