Evidence map›Paper›PMID 41634397›Full record

ArticleJournal of fluorescence2026

A SLC7A5-Specific Near-Infrared Fluorescent Probe for Cancer-Targeted Imaging Applications.

Wei Zhang, Jialin Xu, Liping Dong, Yong Wang, Yang Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei ZhangJiangsu Clinical Medicine Research Institute, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, P.R. China.
Jialin XuDepartment of Oncology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, P.R. China.
Liping DongBiobank, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, P.R. China.
Yong WangDepartment of Thyroid Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, P.R. China. surgwy@jsph.org.cn.
Yang WuBiobank, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, P.R. China. yangwu@njmu.edu.cn.

Funding

the First Affiliated Hospital of Nanjing Medical University Research Fund YNRCQN027the National Natural Science Foundation of China Nos. 81901883, 81801827
6 · The paper itself

Abstract

Extensive surgical resection improves survival in cancer patients. Fluorescence-guided imaging techniques have significantly enhanced the precision of cancer resections. Triple-negative breast cancer (TNBC) lacks expression of the estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2), and no other targetable molecules have been identified. In this study, we verified that the L-type amino acid transporter 1 (LAT1, also known as SLC7A5) is overexpressed in triple-negative breast cancer (TNBC) cells and we constructed a novel near-infrared fluorescent dye Cys-PEG

Indexed as

Fluorescent DyesInfrared RaysLarge Neutral Amino Acid-Transporter 1Optical ImagingTriple Negative Breast NeoplasmsAnimalsCell Line, TumorFemaleFluorescent Chemosensor CompoundsHumansMDA-MB-231 CellsMiceMice, NudeFluorescent Chemosensor CompoundsFluorescent DyesLarge Neutral Amino Acid-Transporter 1SLC7A5 protein, humanCancer imagingFluorescent imagingMethionine (Met)SLC7A5

Identifiers

PMID41634397

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.