Evidence map›Paper›PMID 41635851›Full record

ReviewFrontiers in immunology2025

Macrophage-derived chemokines in T cell regulation: implications for cancer immunotherapy.

Kunpeng Zhang, Jingjing Liu, Qi Liu, Ningning Zhu, Baodong Ye

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Bidirectional Modulation of the Tumor Immune Microenvironment by Gut Microbiota-Derived Indoles: Mechanisms and Therapeutic Potential.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kunpeng ZhangDepartment of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Jingjing LiuDepartment of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Qi LiuDepartment of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Ningning ZhuDepartment of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, China.
Baodong YeDepartment of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophages are pivotal regulators of immunity, with intercellular communication being a central mechanism of their function. Among these communications, chemokines act as critical messengers in macrophage-T cell crosstalk. This review systematically elucidates the notable roles of macrophage-derived chemokines in modulating T cell homeostasis, particularly concentrating on their influence on both CD4

Indexed as

ChemokinesImmunotherapyMacrophagesNeoplasmsT-LymphocytesAnimalsHumansSignal TransductionT-Cell ExhaustionTumor MicroenvironmentChemokinescancer immunotherapychemokinesmacrophagesT cellstumor microenvironment

Identifiers

PMID41635851
PMCPMC12861892

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.