Evidence map›Paper›PMID 41636743›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis.

Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M Frazer, Bing Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shanshan GuoFaculty of Synthetic Biology, Shenzhen University of Advanced Technology, Shenzhen, China.
Yalin WangFaculty of Synthetic Biology, Shenzhen University of Advanced Technology, Shenzhen, China.
Binyu LuFaculty of Synthetic Biology, Shenzhen University of Advanced Technology, Shenzhen, China.
Yu ZhangFaculty of Synthetic Biology, Shenzhen University of Advanced Technology, Shenzhen, China.
David M FrazerMolecular Nutrition Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.
Bing ZhouFaculty of Synthetic Biology, Shenzhen University of Advanced Technology, Shenzhen, China.ORCID https://orcid.org/0000-0002-6585-9284

Funding

China Postdoctoral Science Foundation 2022M723298Guangdong Provincial Key Laboratory of Synthetic Genomics 2023B1212060054Shenzhen Medical Research Fund B2402001
6 · The paper itself

Abstract

Liver fibrosis, driven by excessive collagen synthesis following hepatic injury, poses a significant health challenge. SLC39A13/ZIP13, a recently characterized intracellular iron transporter, is shown to provide iron to the ER/Golgi to help catalyze procollagen hydroxylation during collagen maturation. Here, we investigate whether ZIP13 plays a role during hepatic fibrogenesis modeled by CCl

Indexed as

Cation Transport ProteinsIronLiver CirrhosisAnimalsCollagenDisease Models, AnimalHepatic Stellate CellsLiverMaleMiceMice, KnockoutCation Transport ProteinsCollagenIronSlc39a13 protein, mousecollagenhepatic stellate cellsironliver fibrosisSLC39A13 (ZIP13)VA‐lip‐siRNA

Identifiers

PMID41636743
PMCPMC13067865

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.