ArticleTranslational psychiatry2026
SARS-CoV-2 infection during pregnancy and neurodevelopmental outcomes in early childhood.
Article in Translational psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Prenatal COVID-19 Exposure and Neurodevelopmental and Neurological Disorders in Children.JAMA network open · 2026Article
- Newborn IgG and IgM antibodies to maternal SARS-CoV-2 infection in pregnancy and child neurodevelopmental outcomes.Brain, behavior, and immunity · 2026Article
- Exploring offspring behaviour after prenatal COVID-19 vaccination in mice.Translational psychiatry · 2026Article
- Neuroinflammatory mechanisms and pharmacological advances in autism spectrum disorder: from inflammatory pathways to targeted interventions.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
SARS-CoV-2 infection in pregnancy has become common, yet very little is known about the impact of prenatal exposure on child development. Our objective was to examine the impact of infection with SARS-CoV-2 during pregnancy on child neurodevelopment in the first years of life. We conducted a longitudinal prospective cohort study among a diverse population of 69,987 children born January 2020-September 2021 in Northern California to members of an integrated healthcare system. Maternal SARS-CoV-2 infection during pregnancy was confirmed by polymerase chain reaction (PCR) test. All neurodevelopmental disorders (NDD) diagnosed in children by December 2023 were identified, including autism spectrum disorder (ASD), speech/language delay, and motor delay. Cox proportional hazards regression models estimated hazard ratios (HR) and 95% confidence intervals (CIs), with adjustment for maternal sociodemographic and clinical characteristics, SARS-CoV-2 vaccination status during pregnancy, and child sex. A total of 2777 (3.97%) pregnant individuals had PCR-confirmed SARS-CoV-2 infection during pregnancy. Among 69,987 children aged 27-48 months, 12,006 (17.15%) were diagnosed with NDD; 2724 (3.89%) with ASD, 10,047 (14.36%) with speech/language delay, and 2716 (3.88%) with motor delay. Maternal infection with SARS-CoV-2 during pregnancy was not associated with an increased risk of speech/language delay or motor delay but was associated with an elevated risk of ASD among females (aHR = 1.44, 95% CI 1.05-1.97) but not males (aHR = 1.04, 95% CI 0.83-1.31). Prenatal exposure to SARS-CoV-2 infection may increase risk for autism spectrum disorders among females. Future studies are needed to confirm and extend these findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.