Evidence map›Paper›PMID 41639142›Full record

ArticleScientific reports2026

Patients with tuberculosis and diabetes show altered clinical and biochemical parameters during anti-TB treatment.

Augustine Boadu Asare, Prince Asare, Michelle Yeboah-Manu, Stephen Osei-Wusu, Emelia Danso Konadu, Adwoa Asante-Poku, Yayra Klinogo, Abraham Adjei, Desmond Omane Acheampong, Jane S Afriyie-Mensah and 2 more

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Augustine Boadu Asare *Department of Bacteriology, Noguchi Memorial Institute for Medical Research-University of Ghana, Accra, Ghana.
Prince Asare *Department of Bacteriology, Noguchi Memorial Institute for Medical Research-University of Ghana, Accra, Ghana.
Michelle Yeboah-ManuUniversity of Ghana Medical Center, University of Ghana, Legon, Ghana.
Stephen Osei-WusuDepartment of Bacteriology, Noguchi Memorial Institute for Medical Research-University of Ghana, Accra, Ghana.
Emelia Danso KonaduDepartment of Bacteriology, Noguchi Memorial Institute for Medical Research-University of Ghana, Accra, Ghana.
Adwoa Asante-PokuDepartment of Bacteriology, Noguchi Memorial Institute for Medical Research-University of Ghana, Accra, Ghana.
Yayra KlinogoDepartment of Chest Diseases, Korle-Bu Teaching Hospital, Accra, Ghana.
Abraham AdjeiDepartment of Chest Diseases, Korle-Bu Teaching Hospital, Accra, Ghana.
Desmond Omane AcheampongDepartment of Biomedical Sciences, School of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana.
Jane S Afriyie-MensahDepartment of Chest Diseases, Korle-Bu Teaching Hospital, Accra, Ghana.
Atiase YacobaUniversity of Ghana Medical School, Accra, Ghana.
Dorothy Yeboah-ManuDepartment of Bacteriology, Noguchi Memorial Institute for Medical Research-University of Ghana, Accra, Ghana. dyeboah-manu@noguchi.ug.edu.gh.

Funding

The European and Developing Countries Clinical Trials Partnership (EDCTP2) programme supported by the European Union TMA.2017.GSF.1942-TB-DM
6 · The paper itself

Abstract

Type-2 diabetes mellitus (DM) increases tuberculosis (TB) risk and can worsen treatment outcomes. Both diseases and their treatments induce significant metabolic and biochemical perturbations that influence disease progression and management. This study longitudinally evaluated clinical, metabolic, and serum biochemical changes in patients with pulmonary TB with and without DM before and during anti-TB therapy. Ninety-five adult patients newly diagnosed with pulmonary TB in Ghana were stratified into TB-Only (n = 49; HbA1c < 6.5%) and TB-DM (n = 46; HbA1c ≥ 6.5%) groups, including treated (TB-DMt) and untreated (TB-DMnt) diabetes subgroups. Serum samples collected at baseline (t

Indexed as

Antitubercular AgentsDiabetes Mellitus, Type 2Tuberculosis, PulmonaryAdultFemaleGhanaGlycated HemoglobinHumansHyponatremiaMaleMiddle AgedTreatment OutcomeAntitubercular AgentsGlycated HemoglobinDyslipidemiaHyponatremiaTB-DM comorbidityTreatment outcomesTuberculosisType-2 diabetes mellitus

Identifiers

PMID41639142
PMCPMC12923770

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.