Evidence map›Paper›PMID 41639944›Full record

ArticleRespirology (Carlton, Vic.)2026

Body Composition and Muscle Function in Bronchiectasis: A Comparative Longitudinal Study.

Joice Mara de Oliveira, Amber Smith, Paola D Urroz Guerrero, Laura Cordova Rivera, Dennis Thomas, Vanessa L Clark, Peter G Gibson, Vanessa M McDonald

Abstract readComparative Study
In one paragraph

Article in Respirology (Carlton, Vic.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joice Mara de OliveiraSchool of Nursing and Midwifery, College of Health, Medicine and Wellbeing, The University of Newcastle, Newcastle, New South Wales, Australia.
Amber SmithSchool of Nursing and Midwifery, College of Health, Medicine and Wellbeing, The University of Newcastle, Newcastle, New South Wales, Australia.
Paola D Urroz GuerreroSchool of Nursing and Midwifery, College of Health, Medicine and Wellbeing, The University of Newcastle, Newcastle, New South Wales, Australia.
Laura Cordova RiveraSchool of Sport Exercise and Rehabilitation, Northumbria University, Newcastle upon Tyne, UK.ORCID 0000-0002-1827-8241
Dennis ThomasAsthma and Breathing Research Program, Hunter Medical Research Institute, Newcastle, New South Wales, Australia.ORCID 0000-0003-4182-6821
Vanessa L ClarkSchool of Nursing and Midwifery, College of Health, Medicine and Wellbeing, The University of Newcastle, Newcastle, New South Wales, Australia.
Peter G GibsonAsthma and Breathing Research Program, Hunter Medical Research Institute, Newcastle, New South Wales, Australia.ORCID 0000-0001-5865-489X
Vanessa M McDonaldSchool of Nursing and Midwifery, College of Health, Medicine and Wellbeing, The University of Newcastle, Newcastle, New South Wales, Australia.ORCID 0000-0001-9890-3408

Funding

Hunter Medical Research InstituteUniversity of Newcastle
6 · The paper itself

Abstract

BACKGROUND AND

objectiveAdults with bronchiectasis often present with altered body composition and muscle strength, yet prognostic value of peripheral muscle strength are not well understood. This study compared body composition and muscle function between adults with bronchiectasis and healthy controls and examined whether peripheral muscle strength estimates one-year clinical outcomes.

methodsAdults with HRCT-confirmed bronchiectasis and controls underwent assessments including DXA (body composition), dynamometry (leg and shoulder strength), and core endurance tests. Participants with bronchiectasis were classified as having retained or impaired leg strength based on the 10

resultsSeventy-one participants with bronchiectasis and 92 controls were included; 43 bronchiectasis participants completed follow-up. Females with bronchiectasis had lower appendicular muscle index (p = 0.018) and both sexes had lower bone mineral density compared to their control counterparts (p < 0.001). Osteopenia was 3 times more prevalent in females with bronchiectasis compared to their counterparts (54% versus 18%). Females with bronchiectasis have poorer lateral core endurance than those without (p ≤ 0.003). Leg strength was reduced in bronchiectasis compared to controls, regardless of sex (mean difference [95% CI] for males -25 [-50; -1] Kg and females -18 [-29; -7] Kg). Reduced leg strength is associated with worse dyspnoea, health related quality of life, and functional capacity over one year, explaining up to 33% of the variance (p ≤ 0.001).

conclusionIndividuals with bronchiectasis exhibit impaired muscle function and bone health, with leg strength showing a significant association with clinical outcomes over one year.

Indexed as

Body CompositionBronchiectasisMuscle, SkeletalMuscle StrengthAbsorptiometry, PhotonAdultAgedBone DensityDyspneaExercise ToleranceFemaleHumansLongitudinal StudiesMaleMiddle AgedQuality of Lifeabdominal musclesbronchiectasisdyspnoeaquality of lifeskeletal muscleswalk test

Identifiers

PMID41639944
PMCPMC13125391

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.