Evidence map›Paper›PMID 41641102›Full record

ArticleiScience2026

BCL-11 enables adaptive stress responses to environmental challenges.

Patrizia Niedworok, Rossella Erminia Ciliberti, Beijia Xie, Amal John Mathew, Benjamin Jussila, Jennifer A Lawson, Elena De Domenico, Stefan Paulusch, Marc Beyer, Pierluigi Nicotera and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Patrizia NiedworokGerman Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Rossella Erminia CilibertiGerman Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Beijia XieGerman Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Amal John MathewGerman Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Benjamin JussilaInVivo Biosystems, Eugene, OR 97402, USA.
Jennifer A LawsonInVivo Biosystems, Eugene, OR 97402, USA.
Elena De DomenicoGerman Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Stefan PauluschGerman Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Marc BeyerGerman Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Pierluigi NicoteraGerman Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
N Ahmad AzizGerman Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Dan EhningerGerman Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Sandra BlaessUniversity of Bonn, University Hospital Bonn, Institute of Reconstructive Neurobiology, 53127 Bonn, Germany.
Daniele BanoGerman Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulin/IGF-1 signaling (IIS) is a master regulator of metabolism, stress resilience, and cell homeostasis in multicellular organisms. In the nematode

Indexed as

biological sciencescell biologyhealth sciencesmolecular biology

Identifiers

PMID41641102
PMCPMC12865584

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.