Evidence map›Paper›PMID 41644656›Full record

ArticleScientific reports2026

Eco-friendly synthesis of gold nanoparticles using Gracilaria gracilis with antioxidant potential and biocompatibility.

Kimia Ramezani Moghadam, Sedigheh Gharbi, Aliakbar Haddad-Mashadrizeh, Mohammad Ehsan Taghavizadeh Yazdi

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kimia Ramezani MoghadamDepartment of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran.
Sedigheh GharbiDepartment of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran.
Aliakbar Haddad-MashadrizehDepartment of Industrial Biotechnology, Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran. a.haddad@um.ac.ir.
Mohammad Ehsan Taghavizadeh YazdiApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. metyazdi@gmail.com.ORCID http://orcid.org/0000-0003-0086-8005

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold nanoparticles have emerged as promising materials for drug delivery systems due to their unique biological and physicochemical properties. This study presents the synthesis and biological application of gold nanoparticles using red algae (Gracilaria gracilis) for the first time, offering a cost-effective and eco-friendly method. The biosynthesized nanoparticles (NPs) were characterized using various analytical techniques, including Transmission electron microscopy (TEM), Field emission scanning electron microscopy (FESEM), Energy dispersive X-ray analysis (EDX), UV-Vis-spectroscopy, Powder X-ray diffraction (PXRD), Fourier-transform infrared spectroscopy (FTIR), and Zeta-potential analysis. The UV-Vis spectrum confirmed the successful green synthesis of gold NPs. FESEM and TEM images revealed the spherical morphology of these NPs with an average size of 10.49 nm, and they were uniformly dispersed. The high gold content was further confirmed by EDX analysis. The crystalline size of the nanoparticles, as calculated from XRD data, was about 39.5 nm. The presence of bioactive compounds on the nanoparticles’ surface was verified by FTIR analysis, which also correlated with a decrease in Zeta-potential values. The antioxidant activity was evaluated using the DPPH assay, which revealed dose-dependent radical scavenging effects. Cytotoxicity analysis demonstrated that the biosynthesized gold nanoparticles exhibited no significant toxicity toward human fibroblast cells. Furthermore, these nanoparticles showed excellent biocompatibility, indicating their potential applicability as effective alternatives in biomedical, pharmaceutical, and food industries.

Indexed as

AntioxidantsBiocompatible MaterialsGoldGracilariaMetal NanoparticlesGreen Chemistry TechnologyHumansParticle SizeSpectroscopy, Fourier Transform InfraredX-Ray DiffractionAntioxidantsBiocompatible MaterialsGoldBiocompatibilityBiomedical applicationsGold nanoparticleGreen synthesisRed algae

Identifiers

PMID41644656
PMCPMC12929781

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.