ReviewFrontiers in pharmacology2026
A mini-review: photodynamic therapy-induced immune activation.
Review in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tumors are considered to be among the most significant threats to human health. Immunotherapy, which is achieved through the body's own immune response, shows great potential in the treatment of tumors. Nevertheless, the current low response rate in practical applications still needs to be overcome. Photodynamic therapy (PDT) is a minimally invasive treatment method that generates reactive oxygen species (ROS) through light irradiation of photosensitizers (PSs). It has been demonstrated that PDT is capable of not only efficiently eradicating tumors, but also effectively activating the immune system to recognize and destroy them. In addition, it has been demonstrated that the activation exhibits a persistent anti-tumor effect. It is evident that PDT demonstrates significant potential in the treatment of tumors, the inhibition of metastasis and the prevention of recurrence. This review summarizes the specific mechanisms of PDT-induced immune activation, including innate immunity and adaptive immunity, lists the relevant applications of organic and inorganic PSs in this field, and discusses the next challenges for PDT in tumor immunotherapy.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.